首页
400-620-6333
5`-单磷酸腺嘌呤核苷-唾液酸二钠盐
毒素/淋球菌保护剂；血液调节器
规格或纯度:
≥85%
有货
切换导航
搜索
基本描述
| 规格或纯度 | ≥85% |
|---|---|
| 英文名称 | CMP-Sialic Acid, Monosodium Salt |
| 英文别名 | CMP-N-Acetylneuraminic Acid, Na |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
CMP-唾液酸，钠盐是唾液酸的活性形式。在哺乳动物细胞中，已经证明生物合成含唾液酸的复合碳水化合物是必需的。CMP唾液酸的丢失，单钠盐的产生或CMP唾液酸的反馈抑制剂已导致GLCNE（GNE，UDP-N-乙酰氨基葡糖2-表异构酶/ N-乙酰甘露糖胺激酶）产生克规模的唾液酸。该化合物已显示出通过掩盖结合位点来中和各种毒素的能力。CMP唾液酸单钠盐还通过Galβ1-4GlcNAc基团的唾液酸化作用提供了针对淋球菌的保护作用。通过表面唾液酸转移酶CMP-唾液酸的催化，单钠盐增强了胰岛素的响应性。该化合物还具有调 CMP-sialic acid, Monosodium salt is the active form of sialic acid. In mammalian cells it has been shown to be required for the biosynthesis of sialic acid-containing complex carbohydrates. Loss of CMP sialic acid, Monosodium salt production or the feed back inhibitor of CMP-sialic acid has lead to gram scale production of sialic acid by GLCNE (GNE, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase). The compound has demonstrated the ability to neutralize various toxins through masking binding sites. CMP-sialic acid, Monosodium salt has also provided protection against gonococci by siaylation of Gal beta 1-4GlcNAc group. Catalyzed through a surface sialyl-transferase, CMP-Sialic Acid, Monosodium Salt enhanced the responsiveness of insulin. The compound has also displayed function in blood protein half-life regulation, protection against glycoprotein lysis and cellular adhesion. CMP-Sialic Acid, Monosodium Salt is a substrate of Sialyltransferase. |
名称和标识符
| IUPAC Name | (2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid |
|---|---|
| INCHI | InChI=1S/C20H31N4O16P/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34)/t8-,9?,10+,12+,13?,14+,15+,16+,17+,20+/m0/s1 |
| InChi Key | TXCIAUNLDRJGJZ-HAOOPCFNSA-N |
| Canonical SMILES | CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OP(=O)(O)OCC2C(C(C(O2)N3C=CC(=NC3=O)N)O)O)O |
| PubChem CID | 18292 |
| 分子量 | 636.43 |
化学和物理性质
| 溶解性 | Soluble in water. |
|---|
产品问答
产品问答
上海阿拉丁生化科技股份有限公司
? 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任
危险品化学品经营许可证（带存储）