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1,1'-双(二-叔丁基膦)二茂铁二氯合钯

规格或纯度: 98%
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货号 (SKU) 包装规格 是否现货 价格 数量
B124576-250mg
250mg 现货 Stock Image
B124576-1g
1g 现货 Stock Image
B124576-5g
5g 现货 Stock Image
B124576-10g
10g 期货 Stock Image
B124576-100g
100g 期货 Stock Image

基本描述

规格或纯度 98%
英文名称 1,1'-Bis(di-tert-butylphosphino)ferrocene palladium dichloride
别名 Umicore CX96|[1,1'-双(二叔丁基膦)二茂铁]二氯化钯( II )
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) (PdCl2(dtbpf)) participates as catalyst in Suzuki and Heck reactions. It is a preformed catalyst synthesized by a group of researchers at Johnson Matthey′s Catalysis and Chiral Technologies. It is an active catalyst for various Pd catalyzed cross-coupling reactions.Application Guide for Palladium Catalyzed Cross-Coupling Reactions

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) (PdCl2(dtbpf)) participates as catalyst in Suzuki and Heck reactions. It is a preformed catalyst synthesized by a group of researchers at Johnson Matthey′s Catalysis and Chiral Technologies. It is an active catalyst for various Pd catalyzed cross-coupling reactions.
Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Product class

M-P, Homogeneous Catalysts, M-C, Bidentate Ligands, Ferrocenyl Ligands - Achiral


Reaction type

Cross Coupling Reactions with Arenes, Suzuki-Miyaura Coupling Reaction


Chemical properties

Chemical formula

C26H44Cl2FeP2Pd

Empirical formula

[Pd(dtbpf)Cl2]

Molecular weight

651.75

Metal

Pd

Theoretical metal content

16

Physical state

crystalline

Color

red

Applications & references

Reductive carbonylation of aryl halides as an alternative and mild route for the introduction of aldehyde functionality, which is mostly desired for fine chemical and pharmaceutical intermediates to open up the wide range of further possible transformations.


Reference: Org. Proc. Res. Dev. 2007, 11, 39. (DOI: 10.1021/op060193w)


Total synthesis of diacyl glycerolacyltransferase-1 (DGAT-1) inhibitor including an ambient temperature Suzuki?Miyaura coupling reaction. DGAT-1 is one of two isoforms which catalyze the final and committed step of triglyceride biosynthesis. This compound could play a decisive role in the development of obesity and insulin resistance.?


Reference: Org. Proc. Res. Dev. 2010, 14, 417 (DOI: 10.1021/op900310v)


High yielding Palladium catalyzed C-H arylation of electron-enriched heteroarenes with aryl bromides.


Reference: J. Org. Chem. 2010, 75, 6998. (DOI: 10.1021/jo101433g)

名称和标识符

WGK Germany 3
分子量 651.77

化学和物理性质

熔点 203-208°C

安全和危险性(GHS)

WGK Germany 3
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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参考文献

1. Thomas J Colacot,Helene A Shea.  (2004-10-08)  Cp2Fe(PR2)2PdCl2 (R = i-Pr, t-Bu) complexes as air-stable catalysts for challenging Suzuki coupling reactions..  Organic letters,  ((21)):  (3731-3734).  [PMID:15469335]
2. Bruce H Lipshutz,Tue B Petersen,Alexander R Abela.  (2008-03-14)  Room-temperature Suzuki-Miyaura couplings in water facilitated by nonionic amphiphiles..  Organic letters,  10  ((7)):  (1333-1336).  [PMID:18335944]
3. Bruce H Lipshutz,Benjamin R Taft.  (2008-03-14)  Heck couplings at room temperature in nanometer aqueous micelles..  Organic letters,  10  ((7)):  (1329-1332).  [PMID:18335945]
4. Gabriela A Grasa,Thomas J Colacot.  (2007-11-23)  alpha-arylation of ketones using highly active, air-stable (DtBPF)PdX2 (X = Cl, Br) catalysts..  Organic letters,  ((26)):  (5489-5492).  [PMID:18031054]

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