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药靶配体
天然产物
L-生物喋呤

L-生物喋呤

iNOS活性的辅酶和专性辅因子

规格或纯度: ≥97%

CAS编号: 22150-76-1
分子式: C₉H₁₁N₅O₃
分子量: 237.22
Beilstein号: 87860
EC号: 244-807-8
MDL号: MFCD00036787
PubChem编号: 135403659

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货号 (SKU)	包装规格	是否现货	价格	数量
B120760-5mg	5mg	现货
B120760-25mg	25mg	现货
B120760-100mg	100mg	现货

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基本描述

别名	6-生物喋呤
规格或纯度	≥97%
英文名称	6-Biopterin
生化机理	iNOS活性的辅酶和专性辅因子。通过肾上腺素能循环依赖环磷酸腺苷的机制。神经递质的辅助因子。在体外和体内具有活性。
应用	6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer
储存温度	2-8°C储存
运输条件	冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	Biopterin has two isomers (D- and L-biopterin). We sell only L-Biopterin. The hydrogenated forms of biopterin i.e. dihydrobiopterin and tetrahydrobiopterin are involved in many important biochemical functions in the human body, among which are the hydroxylation of tyrosine, phenylalanine and tryptophan. 6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies sμggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer Biopterin has two isomers (D- and L-biopterin). We sell only L-Biopterin. The hydrogenated forms of biopterin i.e. dihydrobiopterin and tetrahydrobiopterin are involved in many important biochemical functions in the human body, among which are the hydroxylation of tyrosine, phenylalanine and tryptophan. 6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer

名称和标识符

EC号	244-807-8
IUPAC Name	2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3H-pteridin-4-one
INCHI	InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1
InChi Key	LHQIJBMDNUYRAM-DZSWIPIPSA-N
Canonical SMILES	CC(C(C1=CN=C2C(=N1)C(=O)NC(=N2)N)O)O
WGK Germany	3
RTECS	UO3506000
PubChem CID	135403659
分子量	237.22
Beilstein号	87860

化学和物理性质

溶解性	Bioptein is very slightly soluble in water. The solubility of biopterin is about 0.01 g per 100 g of water (220C). Concentrated solutions of biopterin may be prepared using 0.05M NaOH. Ultrasonication may be used to improve dissolution.

安全和危险性（GHS）

象形图	Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation
预防措施声明	P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany	3
RTECS	UO3506000
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

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