氯化钡,二水
规格或纯度:
ACS
- CAS编号: 10326-27-9
- 分子式: BaCl2?2H2O
- 分子量: 244.26
- EC号: 233-788-1
- MDL号: MFCD00149154
- PubChem编号: 5284346
有货
规格或纯度 | ACS |
---|---|
英文名称 | Barium chloride dihydrate |
别名 | 二水合氯化钡 |
生化机理 | Barium chloride produces excitatory effects on neuronal signaling throμgh mobilization of intracellular Ca2+. This has been correlated to causing increases in potential difference and short-circuit currents in stripped sheets of rat intestine with subsequent effects on intestinal secretion. The toxic effects of Ba2+ are mediated throμgh neuronal excitation, and sub-toxic administration of Barium Chloride produces arrhythmias in animals. Barium Chloride-promoted arrhythmias have been employed in studies investigating antiarrhythmic compounds. Barium Chloride demonstrates selective inhibition of MMP-2 (matrix metalloproteinase 2), sμggested to proceed throμgh displacement by Ba2+ of a Ca2+ ion at the catalytic center of MMP-2. |
应用 | 测定硫酸盐和硒酸盐等,色谱分析,点滴分析测定铂,软水剂。织物染色。 |
运输条件 | 常规运输 |
产品介绍 |
味苦咸。微有吸湿性。在100℃时即失去结晶水,但放置在湿空气中又重新吸收二分子结晶水。易溶于水,溶于甲醇,不溶于乙醇、乙酸乙酯和丙酮。中等毒,半数致死量(大鼠,经口)118mg/kg(以无水物计)。测定硫酸盐和硒酸盐等,色谱分析,点滴分析测定铂,软水剂。织物染色。 A soluble salt of barium and source of toxic Ba2+ ions. |
EC号 | 233-788-1 |
---|---|
Canonical SMILES | [Cl-].[Cl-].[Ba+2];[Cl-].[Cl-].O.O.[Ba+2];O.O.Cl[Ba]Cl |
分子式 |
BaCl2?2H2O |
UN Number | 1564 |
PubChem CID | 5284346 |
Packing Group | III |
分子量 | 244.26 |
溶解性 | 易溶于水,溶于甲醇,不溶于乙醇、乙酸乙酯和丙酮。 |
---|---|
密度 | 3.86 |
敏感性 | 对湿度敏感 |
熔点 | 963°C |
折光率 | 1.635 |
一般危化品 | 一般危化品 |
---|---|
象形图 |
Toxic |
信号词 | Danger |
危险声明 |
H319: Causes serious eye irritation H301: Toxic if swallowed H332: Harmful if inhaled |
预防措施声明 | P261,P305+P351+P338,P280,P301+P310,P405,P501,P312,P264,P271,P270,P304+P340,P337+P313,P330 |
WGK Germany | 1 |
RTECS | CQ8751000 |
个人防护装备 | Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges |
1. Goodfellow NM, Bailey CD, Lambe EK. (2012) The native serotonin 5-HT(5A) receptor: electrophysiological characterization in rodent cortex and 5-HT(1A)-mediated compensatory plasticity in the knock-out mouse.. J Neurosci, 32 (17): (5804-9). [PMID:22539842] |
2. Merriam LA et al.. (2013) Pituitary adenylate cyclase 1 receptor internalization and endosomal signaling mediate the pituitary adenylate cyclase activating polypeptide-induced increase in guinea pig cardiac neuron excitability.. J Neurosci, 33 (10): (4614-22). [PMID:23467377] |
3. Chiara Callies,Johannes Fels,Ivan Liashkovich,Katrin Kliche,Pia Jeggle,Kristina Kusche-Vihrog,Hans Oberleithner. (2011-05-12) Membrane potential depolarization decreases the stiffness of vascular endothelial cells.. Journal of cell science, 124 ((Pt 11)): (1936-1942). [PMID:21558418] |
4. Hyung Seok Ahn,Ike dela Pe?a,Yong Chul Kim,Jae Hoon Cheong. (2011-06-08) 4-Chloro-7-trifluoromethyl-10H- benzo[4,5]furo[3,2-b]indole-1-carboxylic acid (TBIC), a putative BK(Ca) channel opener with uterine relaxant activities.. Pharmacology, 87 ((5-6)): (331-340). [PMID:21646818] |
5. F Borrelli,R Capasso,B Severino,F Fiorino,G Aviello,G De Rosa,M Mazzella,B Romano,F Capasso,I Fasolino,A A Izzo. (2011-06-22) Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice.. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 23 ((8)): (745-e331-745-e331). [PMID:21689210] |
6. Haiyan Lu,Danping Huang,Richard M Ransohoff,Lan Zhou. (2011-06-24) Acute skeletal muscle injury: CCL2 expression by both monocytes and injured muscle is required for repair.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 25 ((10)): (3344-3355). [PMID:21697550] |
7. Jun-Yih Chen,Min-Chi Jiang,Li-Wen Chu,Su-Ling Hsieh,Ing-Jun Chen,Bin-Nan Wu. (2012-01-03) KMUP-1 inhibits L-type Ca2? channels involved the protein kinase C in rat basilar artery myocytes.. The Kaohsiung journal of medical sciences, 27 ((12)): (538-543). [PMID:22208536] |
8. Virginia Bay,Arthur M Butt. (2012-02-01) Relationship between glial potassium regulation and axon excitability: a role for glial Kir4.1 channels.. Glia, 60 ((4)): (651-660). [PMID:22290828] |
9. Puneet Mahajan,Reza Tabrizchi. (2012-03-24) Influence of hyperpolarization caused by high salt diet on β-adrenoceptor-mediated responses in rat pulmonary artery.. Journal of cardiovascular pharmacology, 60 ((1)): (23-32). [PMID:22441303] |
10. Mirna González-González,Karla Mayolo-Deloisa,Marco Rito-Palomares. (2012-03-27) PEGylation, detection and chromatographic purification of site-specific PEGylated CD133-Biotin antibody in route to stem cell separation.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 893-894 (): (182-186). [PMID:22445308] |
11. Michaela E Levin,Jeffrey R Holt. (2012-04-13) The function and molecular identity of inward rectifier channels in vestibular hair cells of the mouse inner ear.. Journal of neurophysiology, 108 ((1)): (175-186). [PMID:22496522] |
12. E P Sivolodski?. (2012-05-29) [Method for bacterial sensitivity determination towards barium ions – taxonomic marker of Pseudomonas genus].. Mikrobiologiia, 81 ((1)): (120-125). [PMID:22629689] |
13. Daniel Hagenfeld,Beatrice Borkenhagen,Tobias Schulz,Hermann Schillers,Udo Schumacher,Peter Prehm. (2012-06-16) Hyaluronan export through plasma membranes depends on concurrent K+ efflux by K(ir) channels.. PloS one, 7 ((6)): (e39096-e39096). [PMID:22701748] |
14. Amr Ali Mohamed,Egon Matijevi?. (2012-06-19) Preparation and characterization of uniform particles of flufenamic acid and its calcium and barium salts.. Journal of colloid and interface science, 381 ((1)): (198-201). [PMID:22703985] |
15. Hanna Heikkinen,Frans Vinberg,Marja Pitk?nen,Bertel Kommonen,Ari Koskelainen. (2012-06-30) Flash responses of mouse rod photoreceptors in the isolated retina and corneal electroretinogram: comparison of gain and kinetics.. Investigative ophthalmology & visual science, 53 ((9)): (5653-5664). [PMID:22743325] |
16. Anne R Crecelius,Brett S Kirby,Gary J Luckasen,Dennis G Larson,Frank A Dinenno. (2012-07-11) ATP-mediated vasodilatation occurs via activation of inwardly rectifying potassium channels in humans.. The Journal of physiology, 590 ((21)): (5349-5359). [PMID:22777673] |
17. Gisela Di Giusto,Pilar Flamenco,Valeria Rivarola,Juan Fernández,Luciana Melamud,Paula Ford,Claudia Capurro. (2012-07-13) Aquaporin 2-increased renal cell proliferation is associated with cell volume regulation.. Journal of cellular biochemistry, 113 ((12)): (3721-3729). [PMID:22786728] |
18. Michael Xavier Doss,José M Di Diego,Robert J Goodrow,Yuesheng Wu,Jonathan M Cordeiro,Vladislav V Nesterenko,Héctor Barajas-Martínez,Dan Hu,Janire Urrutia,Mayurika Desai,Jacqueline A Treat,Agapios Sachinidis,Charles Antzelevitch. (2012-07-21) Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).. PloS one, 7 ((7)): (e40288-e40288). [PMID:22815737] |
19. Chung-Lin Wang,Mei-Ling Tsai,Sheng-Nan Wu. (2012-08-03) Evidence for mitoxantrone-induced block of inwardly rectifying K(+) channels expressed in the osteoclast precursor RAW 264.7 cells differentiated with lipopolysaccharide.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 30 ((3)): (687-701). [PMID:22854649] |
20. Fan Hu,Chi Man Koon,Judy Yuet Wa Chan,Kit Man Lau,Y W Kwan,Kwok Pui Fung. (2012-08-15) Involvements of calcium channel and potassium channel in Danshen and Gegen decoction induced vasodilation in porcine coronary LAD artery.. Phytomedicine : international journal of phytotherapy and phytopharmacology, 19 ((12)): (1051-1058). [PMID:22889578] |
21. Javed Khan,Muhammad Farid Khan,Syed Umer Jan,Haroon Khan,Asimur Rehman. (2012-09-27) Study of the effects of BaCl(2) on the level of glutathione in plasma and cytosolic fraction in whole blood.. Pakistan journal of pharmaceutical sciences, 25 ((4)): (883-888). [PMID:23010010] |
22. Fábia Valéria M Souza,Marcelly Barbosa da Rocha,Dami?o P de Souza,Rosilene Moretti Mar?al. (2012-10-30) (-)-Carvone: antispasmodic effect and mode of action.. Fitoterapia, 85 (): (20-24). [PMID:23103297] |
23. Caroline Zanotto,Renata Torres Abib,Cristiane Batassini,Lucas Silva Tortorelli,Regina Biasibetti,Letícia Rodrigues,Patrícia Nardin,Fernanda Hansen,Carmem Gottfried,Marina Concli Leite,Carlos-Alberto Gon?alves. (2012-11-13) Non-specific inhibitors of aquaporin-4 stimulate S100B secretion in acute hippocampal slices of rats.. Brain research, 1491 (): (14-22). [PMID:23142267] |
24. Steven J Kehl,David Fedida,Zhuren Wang. (2012-12-18) External Ba(2+) block of Kv4.2 channels is enhanced in the closed-inactivated state.. American journal of physiology. Cell physiology, 304 ((4)): (C370-C381). [PMID:23242186] |
25. Eugen J Verspohl,Hajime Fujii,Kohei Homma,Sybille Buchwald-Werner. (2013-01-30) Testing of Perilla frutescens extract and Vicenin 2 for their antispasmodic effect.. Phytomedicine : international journal of phytotherapy and phytopharmacology, 20 ((5)): (427-431). [PMID:23357362] |
26. Patcharin Tep-Areenan,Sunit Suksamrarn. (2013-03-22) Mechanisms of vasorelaxation to gamma-mangostin in the rat aorta.. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 95 Suppl 12 (): (S63-S68). [PMID:23513467] |
27. Anja Veronovski,Zeljko Knez,Zoran Novak. (2013-07-16) Comparison of ionic and non-ionic drug release from multi-membrane spherical aerogels.. International journal of pharmaceutics, 454 ((1)): (58-66). [PMID:23850813] |
28. Ying Lv,Li-Li Tang,Jia-Kai Wei,Xue-Feng Xu,Weizhong Gu,Lin-Chen Fu,Li-Yan Zhang,Li-Zhong Du. (2013-10-01) Decreased Kv1.5 expression in intrauterine growth retardation rats with exaggerated pulmonary hypertension.. American journal of physiology. Lung cellular and molecular physiology, 305 ((11)): (L856-L865). [PMID:24077947] |
29. Eiji Ohmae,Yurina Miyashita,Shin-Ichi Tate,Kunihiko Gekko,Soichiro Kitazawa,Ryo Kitahara,Kunihiro Kuwajima. (2013-10-22) Solvent environments significantly affect the enzymatic function of Escherichia coli dihydrofolate reductase: comparison of wild-type protein and active-site mutant D27E.. Biochimica et biophysica acta, 1834 ((12)): (2782-2794). [PMID:24140567] |
30. Rajani M George,Stefano Biressi,Brian J Beres,Erik Rogers,Amanda K Mulia,Ronald E Allen,Alan Rawls,Thomas A Rando,Jeanne Wilson-Rawls. (2013-10-31) Numb-deficient satellite cells have regeneration and proliferation defects.. Proceedings of the National Academy of Sciences of the United States of America, 110 ((46)): (18549-18554). [PMID:24170859] |
31. Pimluck Kijjanapanich,Ajit P Annachhatre,Giovanni Esposito,Piet N L Lens. (2014-06-25) Chemical sulphate removal for treatment of construction and demolition debris leachate.. Environmental technology, 35 ((13-16)): (1989-1996). [PMID:24956793] |
32. Diana Zhang,Terry Huang,Philip S Lukeman,Paul J Paukstelis. (2014-11-13) Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad.. Nucleic acids research, 42 ((21)): (13422-13429). [PMID:25389267] |
33. Tieyuan Zhang,Daniel Bain,Richard Hammack,Radisav D Vidic. (2015-02-03) Analysis of radium-226 in high salinity wastewater from unconventional gas extraction by inductively coupled plasma-mass spectrometry.. Environmental science & technology, 49 ((5)): (2969-2976). [PMID:25642997] |
34. Laurence D Picton,Keith T Sillar. (2016-10-21) Mechanisms underlying the endogenous dopaminergic inhibition of spinal locomotor circuit function in Xenopus tadpoles.. Scientific reports, 6 (): (35749-35749). [PMID:27760989] |
35. David D Bushart,Ravi Chopra,Vikrant Singh,Geoffrey G Murphy,Heike Wulff,Vikram G Shakkottai. (2018-03-22) Targeting potassium channels to treat cerebellar ataxia.. Annals of clinical and translational neurology, 5 ((3)): (297-314). [PMID:29560375] |
36. Qian Wang,F M Zhou. (2019-01-20) cAMP-producing chemogenetic and adenosine A2a receptor activation inhibits the inwardly rectifying potassium current in striatal projection neurons.. Neuropharmacology, 148 (): (229-243). [PMID:30659840] |
37. Yasmine Kamen,Ragnhildur Thóra Káradóttir. (2021-04-27) Combining whole-cell patch clamp and dye loading in acute brain slices with bulk RNA sequencing in embryonic to aged mice.. STAR protocols, 2 ((2)): (100439-100439). [PMID:33899020] |
38. Bokyung Song,Sung-Joong Lee,Chong-Hyun Kim. (2021-07-03) Roles of Cytokines in the Temporal Changes of Microglial Membrane Currents and Neuronal Excitability and Synaptic Efficacy in ATP-Induced Cortical Injury Model.. International journal of molecular sciences, 22 ((13)): (). [PMID:34202215] |