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BRIJ?O20聚氧乙烯20油醚

规格或纯度: average Mn ~1,150
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货号 (SKU) 包装规格 是否现货 价格 数量
B107104-25g 25g 现货 Stock Image
B107104-100g 100g 现货 Stock Image
B107104-500g 500g 现货 Stock Image
B107104-2.5kg 2.5kg 现货 Stock Image
B107104-10kg 10kg 现货 Stock Image
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聚合物/高分子试剂 醇
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基本描述

规格或纯度 average Mn ~1,150
英文名称 BRIJ?O20
别名 聚氧乙烯月桂醚；聚乙二醇单油醚 (n=约20)
英文别名 Polyethylene Glycol Monooleyl Ether; Polyoxyethylene 20 oleyl ether
法律信息 Brij is a registered trademark of Croda International PLC
运输条件 常规运输
产品介绍

The Brij O range are primary O/W emulsifiers, particularly suited to emulsifying unsaturated fatty acids. Suitable for the formulation of microemulsion gels as primary emulsifiers or as co-emulsifiers paired with the Crodafos phosphate esters. They are solubilising, dispersing, spreading, wetting and gelling agents. Brij O20 has been found to be an extremely effective solubiliser for lipophilic vitamins and oil soluble actives. It is effective at remarkably low inclusion ratios of between 2:1 and 5:1 depending on the oil. Recommended topical usage levels of 0.5-10%. Chemical/Monograph description Macrogol Oleyl Ether PhEur (PEG 20 Oleyl Ether, Oleth-20) 产品生产厂家：英国禾大（Croda）

The Brij O range are primary O/W emulsifiers, particularly suited to emulsifying unsaturated fatty acids. Suitable for the formulation of microemulsion gels as primary emulsifiers or as co-emulsifiers paired with the Crodafos phosphate esters. They are solubilising, dispersing, spreading, wetting and gelling agents. Brij O20 has been found to be an extremely effective solubiliser for lipophilic vitamins and oil soluble actives. It is effective at remarkably low inclusion ratios of between 2:1 and 5:1 depending on the oil. Recommended topical usage levels of 0.5-10%. Chemical/Monograph description Macrogol Oleyl Ether PhEur (PEG 20 Oleyl Ether, Oleth-20) Manufacturer：Croda

名称和标识符

分子式

C18H35(OCH2CH2)nOH
PubChem CID 5364713

化学和物理性质

密度 0.9
沸点 100°C
熔点 30°C
折光率 1.4600 to 1.4640
闪点(℃) 150°C

安全信息

象形图
ghs09

Environmental Hazard

ghs07

Harmful
信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H303: May be harmful if swallowed
预防措施声明 P305+P351+P338,P280,P302+P352,P312,P264,P337+P313,P362+P364,P332+P313
WGK Germany 2
RTECS RK2775000
个人防护装备 Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

参考文献

1. Prapaporn Boonme,Karen Krauel,Anja Graf,Thomas Rades,Varaporn Buraphacheep Junyaprasert.  (2006-06-27)  Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate/water/Brij 97:1-butanol..  AAPS PharmSciTech,  7  ((2)):  (E45-E45).  [PMID:16796362]
2. Majid Tabbakhian,Naser Tavakoli,Mahmoud Reza Jaafari,Saeid Daneshamouz.  (2006-07-14)  Enhancement of follicular delivery of finasteride by liposomes and niosomes 1. In vitro permeation and in vivo deposition studies using hamster flank and ear models..  International journal of pharmaceutics,  323  ((1-2)):  (1-10).  [PMID:16837150]
3. Carles Gil,Roger Cubí,Juan Blasi,José Aguilera.  (2006-08-22)  Synaptic proteins associate with a sub-set of lipid rafts when isolated from nerve endings at physiological temperature..  Biochemical and biophysical research communications,  348  ((4)):  (1334-1342).  [PMID:16920068]
4. Ahmed S Zidan,Omaima A Sammour,Mohammed A Hammad,Nagia A Megrab,Muhammad J Habib,Mansoor A Khan.  (2006-12-16)  Quality by design: understanding the formulation variables of a cyclosporine A self-nanoemulsified drug delivery systems by Box-Behnken design and desirability function..  International journal of pharmaceutics,  332  ((1-2)):  (55-63).  [PMID:17169518]
5. K Rieber,J Sykora,A Olzyńska,R Jelinek,G Cevc,M Hof.  (2007-02-16)  The use of solvent relaxation technique to investigate headgroup hydration and protein binding of simple and mixed phosphatidylcholine/surfactant bilayer membranes..  Biochimica et biophysica acta,  1768  ((5)):  (1050-1058).  [PMID:17300743]
6. Ross A Kennedy,Michelle L Kennedy.  (2007-04-06)  Effect of selected non-ionic surfactants on the flow behavior of aqueous veegum suspensions..  AAPS PharmSciTech,  8  ((1)):  (25-25).  [PMID:17408224]
7. R B Shah,A S Zidan,T Funck,M A Tawakkul,A Nguyenpho,M A Khan.  (2007-05-25)  Quality by design: characterization of self-nano-emulsified drug delivery systems (SNEDDs) using ultrasonic resonator technology..  International journal of pharmaceutics,  341  ((1-2)):  (189-194).  [PMID:17521836]
8. Myriam Chentouf,Soufiane Ghannam,Cédric Bès,Samuel Troadec,Martine Cérutti,Thierry Chardès.  (2007-06-21)  Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains..  Journal of immunology (Baltimore, Md. : 1950),  179  ((1)):  (409-420).  [PMID:17579062]
9. Varaporn Buraphacheep Junyaprasert,Prapaporn Boonme,Sarunyoo Songkro,Karen Krauel,Thomas Rades.  (2007-08-31)  Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions..  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques,  10  ((3)):  (288-298).  [PMID:17727792]
10. Sang-Chul Shin,Jin Kim,Woong-Jang Kim,Seong-Jin Kim,Cheong-Weon Cho.  (2007-10-27)  Development and biopharmaceutical evaluation of quinupramine-EVA matrix containing penetration enhancer for the enhanced transdermal absorption in rats..  Pharmaceutical development and technology,  12  ((5)):  (429-436).  [PMID:17963142]
11. Yash Kapoor,Anuj Chauhan.  (2008-03-25)  Drug and surfactant transport in Cyclosporine A and Brij 98 laden p-HEMA hydrogels..  Journal of colloid and interface science,  322  ((2)):  (624-633).  [PMID:18359493]
12. Marina Shevachman,Nissim Garti,Arnon Shani,Amnon C Sintov.  (2008-04-11)  Enhanced percutaneous permeability of diclofenac using a new U-type dilutable microemulsion..  Drug development and industrial pharmacy,  34  ((4)):  (403-412).  [PMID:18401782]
13. Yash Kapoor,Anuj Chauhan.  (2008-06-26)  Ophthalmic delivery of Cyclosporine A from Brij-97 microemulsion and surfactant-laden p-HEMA hydrogels..  International journal of pharmaceutics,  361  ((1-2)):  (222-229).  [PMID:18577433]
14. Sergey Filippov,Martin Hruby,Cestmír Konák,Hana Macková,Milena Spírková,Petr Stepánek.  (2008-08-09)  Novel pH-responsive nanoparticles..  Langmuir : the ACS journal of surfaces and colloids,  24  ((17)):  (9295-9301).  [PMID:18686981]
15. Woraporn Sukhumavasi,Charlotte E Egan,Amy L Warren,Gregory A Taylor,Barbara A Fox,David J Bzik,Eric Y Denkers.  (2008-08-21)  TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite..  Journal of immunology (Baltimore, Md. : 1950),  181  ((5)):  (3464-3473).  [PMID:18714019]
16. Doaa Ahmed El-Setouhy,Sahar Mohy Ahmed El-Ashmony.  (2010-08-21)  Ketorolac trometamol topical formulations: release behaviour, physical characterization, skin permeation, efficacy and gastric safety..  The Journal of pharmacy and pharmacology,  62  ((1)):  (25-34).  [PMID:20722996]
17. Gladious Naguib El-Hadidy,Howida Kamal Ibrahim,Magdi Ibrahim Mohamed,Mohamed Farid El-Milligi.  (2011-06-24)  Microemulsions as vehicles for topical administration of voriconazole: formulation and in vitro evaluation..  Drug development and industrial pharmacy,  38  ((1)):  (64-72).  [PMID:21696340]
18. Jessica Phelps,M Vitória L B Bentley,Luciana B Lopes.  (2011-06-28)  In situ gelling hexagonal phases for sustained release of an anti-addiction drug..  Colloids and surfaces. B, Biointerfaces,  87  ((2)):  (391-398).  [PMID:21703826]
19. María Vergara-Barberán,Aarón Escrig-Doménech,María Jesús Lerma-García,Ernesto Francisco Simó-Alfonso,José Manuel Herrero-Martínez.  (2011-09-13)  Capillary electrophoresis of free fatty acids by indirect ultraviolet detection: application to the classification of vegetable oils according to their botanical origin..  Journal of agricultural and food chemistry,  59  ((20)):  (10775-10780).  [PMID:21905655]
20. Lucia Montenegro,Chiara Sinico,Ines Castangia,Claudia Carbone,Giovanni Puglisi.  (2012-06-05)  Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation..  International journal of pharmaceutics,  434  ((1-2)):  (169-174).  [PMID:22659127]
21. Gurpreet Kaur,Leonardo Chiappisi,Sylvain Prévost,Ralf Schweins,Michael Gradzielski,Surinder K Mehta.  (2012-06-23)  Probing the microstructure of nonionic microemulsions with ethyl oleate by viscosity, ROESY, DLS, SANS, and cyclic voltammetry..  Langmuir : the ACS journal of surfaces and colloids,  28  ((29)):  (10640-10652).  [PMID:22720716]
22. Maria E N P Ribeiro,Carolina L de Moura,Mariano G S Vieira,Nilce V Gramosa,Chiraphon Chaibundit,Marcos C de Mattos,David Attwood,Stephen G Yeates,S Keith Nixon,Nágila M P S Ricardo.  (2012-07-31)  Solubilisation capacity of Brij surfactants..  International journal of pharmaceutics,  436  ((1-2)):  (631-635).  [PMID:22842626]
23. Claudia Salerno,Sebastian Perez,Ezequiel Monteagudo,Adriana Carlucci,Carlos Bregni.  (2012-12-25)  Solubility of amphotericin B in water-lecithin-dispersions and lecithin-based submicron emulsions..  Pakistan journal of pharmaceutical sciences,  26  ((1)):  (189-193).  [PMID:23261747]
24. Ji Won Park,James R Reed,Lauren M Brignac-Huber,Wayne L Backes.  (2014-09-23)  Cytochrome P450 system proteins reside in different regions of the endoplasmic reticulum..  The Biochemical journal,  464  ((2)):  (241-249).  [PMID:25236845]
25. Chuanyu Yang,Charles A Powell,Yongping Duan,Robert Shatters,Muqing Zhang.  (2015-07-25)  Antimicrobial Nanoemulsion Formulation with Improved Penetration of Foliar Spray through Citrus Leaf Cuticles to Control Citrus Huanglongbing..  PloS one,  10  ((7)):  (e0133826-e0133826).  [PMID:26207823]
26. Jia-You Fang,Chi-Feng Hung,Mei-Hui Liao,Chih-Chen Chien.  (2007-02-27)  A study of the formulation design of acoustically active lipospheres as carriers for drug delivery..  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,  67  ((1)):  (67-75).  [PMID:17320362]
27. Xi Chen,M Jayne Lawrence,David J Barlow,Roger J Morris,Richard K Heenan,Peter J Quinn.  (2009-01-03)  The structure of detergent-resistant membrane vesicles from rat brain cells..  Biochimica et biophysica acta,  1788  ((2)):  (477-483).  [PMID:19118517]
28. Jingling Tang,Yongjun Wang,Dun Wang,Yuhua Wang,Zhenghong Xu,Kelly Racette,Feng Liu.  (2013-01-15)  Key structure of brij for overcoming multidrug resistance in cancer..  Biomacromolecules,  14  ((2)):  (424-430).  [PMID:23311629]

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