| 规格或纯度 | ≥98%(HPLC) |
|---|---|
| 英文名称 | AH 11110 hydrochloride |
| 别名 | 4-氨基-1-(2-苯基苯氧基)-4-哌啶丁烷-2-醇盐酸盐 |
| 英文别名 | AH 11110 HYDROCHLORIDE|179388-65-9|AH 11110|AH 11110A|AH11110A;AH-11110A|4-imino-1-(2-phenylphenoxy)-4-piperidin-1-ylbutan-2-ol hydrochloride|1-Piperidinepropanol, alpha-[([1,1'-biphenyl]-2-yloxy)methyl]-gamma-imino-, hydrochloride (1:1)|AH11110|AH-11110| |
| 生化机理 | α1B-肾上腺素受体的亚型选择性配体。与表达α1B（仓鼠），α1A（牛）和α1D（大鼠）的成纤维细胞膜结合的pKi值分别为7.1、5.59和5.68。在平滑肌制剂中似乎在α1亚型和α2受体之间是非选择性的。 |
| 储存温度 | 室温 |
| 运输条件 | 常规运输 |
| IUPAC Name | 4-imino-1-(2-phenylphenoxy)-4-piperidin-1-ylbutan-2-ol;hydrochloride |
|---|---|
| INCHI | InChI=1S/C21H26N2O2.ClH/c22-21(23-13-7-2-8-14-23)15-18(24)16-25-20-12-6-5-11-19(20)17-9-3-1-4-10-17;/h1,3-6,9-12,18,22,24H,2,7-8,13-16H2;1H |
| InChi Key | WWHGFIXWBLHHQB-UHFFFAOYSA-N |
| Canonical SMILES | C1CCN(CC1)C(=N)CC(COC2=CC=CC=C2C3=CC=CC=C3)O.Cl |
| PubChem CID | 9907616 |
| 分子量 | 374.91 |
| 溶解性 | 溶于water, 最高浓度 (mg/mL): None, 最高浓度(mM): 25 |
|---|
| Ligand ID | 8461 |
|---|---|
| 名称 | AH 11110 |
| 别名 | AH11110 |
| 类别 | Synthetic organic |
| 学名 | 4-imino-1-(2-phenylphenoxy)-4-piperidin-1-ylbutan-2-ol hydrochloride |
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
| 评价 | Sulfadimidine (sulfamethazine) is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth. |
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