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11-叠氮-3,6,9-三氧杂十一烷-1-胺

规格或纯度: 98%
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A122192-200mg 200mg 现货 Stock Image
A122192-1g 1g 现货 Stock Image
A122192-5g 5g 现货 Stock Image
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PEG化试剂 官能团化合物
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基本描述

规格或纯度 98%
英文名称 11-Azido-3,6,9-trioxaundecan-1-amine
别名 1-氨基-11-叠氮-3,6,9-三氧杂十一烷
英文别名 Azido-PEG3-amine;N3-PEG3-CH2CH2NH2;1-Amino-11-azido-3,6,9-trioxaundecane;11-Amino-3,6,9-trioxaundecanyl Azide;2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethylamine;O-(2-Aminoethyl)-O′-(2-azidoethyl)diethylene glycol
储存温度 2-8°C储存,充氩
运输条件 冰袋运输
产品介绍

1-Amino-11-azido-3,6,9-trioxaundecane is a PEG derivative, which contains a free amine that can be conjμgated to biological molecules directly by an amide linkage and an azide that can be reduced to an amine for conjμgation to other molecules.A PEG derivative used as a bifunctional, hydrophilic linker

1-Amino-11-azido-3,6,9-trioxaundecane is a PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage and an azide that can be reduced to an amine for conjugation to other molecules. 11-Azido-3,6,9-trioxaundecan-1-amine is an azide with polyethylene glycol-like characteristics that can be used to prepare azide-functionalized polymers via click reaction
A PEG derivative used as a bifunctional, hydrophilic linker

名称和标识符

IUPAC Name 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanamine
INCHI InChI=1S/C8H18N4O3/c9-1-3-13-5-7-15-8-6-14-4-2-11-12-10/h1-9H2
InChi Key FPVCVHVTMPCZTH-UHFFFAOYSA-N
Canonical SMILES C(COCCOCCOCCN=[N+]=[N-])N
分子式

C8H18N4O3
PubChem CID 2735280
Beilstein号 4745506
分子量 218.25

化学和物理性质

密度 1.1
敏感性 对热，光线和空气敏感
折光率 1.47

安全信息

象形图
ghs05

Corrosive
信号词 Danger
危险声明 H314: Causes severe skin burns and eye damage
预防措施声明 P280,P321,P405,P501,P264,P260,P301+P330+P331,P304+P340,P363,P305+P354+P338,P302+P361+P354,P316
WGK Germany 3
Reaxy-Rn 4745506
个人防护装备 Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

参考文献

1. Brudno Y et al..  (2018)  Replenishable drug depot to combat post-resection cancer recurrence..  Biomaterials,    ():  ().  [PMID:29779862]
2. Patrick Dennler,Laura K Bailey,Philipp R Spycher,Roger Schibli,Eliane Fischer.  (2015-02-18)  Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms..  Chembiochem : a European journal of chemical biology,  16  ((5)):  (861-867).  [PMID:25688874]
3. Shigehito Osawa,Kensuke Osada,Shigehiro Hiki,Anjaneyulu Dirisala,Takehiko Ishii,Kazunori Kataoka.  (2015-12-20)  Polyplex Micelles with Double-Protective Compartments of Hydrophilic Shell and Thermoswitchable Palisade of Poly(oxazoline)-Based Block Copolymers for Promoted Gene Transfection..  Biomacromolecules,  17  ((1)):  (354-361).  [PMID:26682466]
4. Brittany L Hartwell,Chad J Pickens,Martin Leon,Cory Berkland.  (2017-05-06)  Multivalent Soluble Antigen Arrays Exhibit High Avidity Binding and Modulation of B Cell Receptor-Mediated Signaling to Drive Efficacy against Experimental Autoimmune Encephalomyelitis..  Biomacromolecules,  18  ((6)):  (1893-1907).  [PMID:28474886]
5. Victor R Mann,Alexander S Powers,Drew C Tilley,Jon T Sack,Bruce E Cohen.  (2018-04-03)  Azide-Alkyne Click Conjugation on Quantum Dots by Selective Copper Coordination..  ACS nano,  12  ((5)):  (4469-4477).  [PMID:29608274]
6. Shota Konno,Taisuke Banno,Hideaki Takagi,Satoshi Honda,Taro Toyota.  (2018-08-28)  Irreversible aggregation of alternating tetra-block-like amphiphile in water..  PloS one,  13  ((8)):  (e0202816-e0202816).  [PMID:30148887]
7. Claudia Arndt,Anja Feldmann,Stefanie Koristka,Martin Sch?fer,Ralf Bergmann,Nicola Mitwasi,Nicole Berndt,Dominik Bachmann,Alexandra Kegler,Marc Schmitz,Edinson Puentes-Cala,Javier Andrés Soto,Gerhard Ehninger,Jens Pietzsch,Christos Liolios,Gerd Wunderlich,J?rg Kotzerke,Klaus Kopka,Michael Bachmann.  (2019-10-28)  A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR..  Oncoimmunology,  8  ((11)):  (1659095-1659095).  [PMID:31646084]
8. Hua Wang,Miguel C Sobral,Tracy Snyder,Yevgeny Brudno,Vijay S Gorantla,David J Mooney.  (2019-11-07)  Clickable, acid labile immunosuppressive prodrugs for in vivo targeting..  Biomaterials science,  8  ((1)):  (266-277).  [PMID:31690897]
9. Ming Fan,Ye Ma,Jiahui Mao,Ziwei Zhang,Huaping Tan.  (2015-04-04)  Cytocompatible in situ forming chitosan/hyaluronan hydrogels via a metal-free click chemistry for soft tissue engineering..  Acta biomaterialia,  20  ():  (60-68).  [PMID:25839124]
10. Brittany L Hartwell,Chad J Pickens,Martin Leon,Laura Northrup,Matthew A Christopher,J Daniel Griffin,Francisco Martinez-Becerra,Cory Berkland.  (2018-07-17)  Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis..  Journal of autoimmunity,  93  ():  (76-88).  [PMID:30007842]
11. J Daniel Griffin,Martin A Leon,Jean R Salash,Michael Shao,Brittany L Hartwell,Chad J Pickens,Joshua O Sestak,Cory Berkland.  (2019-04-19)  Acute B-Cell Inhibition by Soluble Antigen Arrays Is Valency-Dependent and Predicts Immunomodulation in Splenocytes..  Biomacromolecules,  20  ((5)):  (2115-2122).  [PMID:30995843]
12. Dana Al Sulaiman,Jason Y H Chang,Nitasha R Bennett,Helena Topouzi,Claire A Higgins,Darrell J Irvine,Sylvain Ladame.  (2019-08-15)  Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid..  ACS nano,  13  ((8)):  (9620-9628).  [PMID:31411871]

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