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阿斯巴甜

天门冬氨酸/苯丙氨酸二肽甲酯
规格或纯度: 98%
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货号 (SKU) 包装规格 是否现货 价格 数量
A113247-5g 5g 现货 Stock Image
A113247-25g 25g 现货 Stock Image
A113247-100g 100g 现货 Stock Image
A113247-500g 500g 现货 Stock Image
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基本描述

规格或纯度 98%
英文名称 Aspartame
别名 天冬甜素
英文别名 N-L-α-Aspartyl-L-phenylalanine 1-Methyl Ester; H-Asp-Phe-OMe; L-Aspartyl-L-phenylalanine methyl ester; L-Aspartyl-L-phenylalanine methyl ester; Asp-Phe methyl ester N-L-alpha-Aspartyl-L-phenylalanine 1-Methyl Ester L-Aspartyl-L-phenylalanine methyl ester
生化机理 Asp-Phe methyl ester (Asp-Phe-OMe) is used as a synthetic sweeter, sμgar substitute. Asp-Phe methyl ester is being studied for a variety of potential benefits as a nutrition supplement, such as the delay of osteoarthritis and modulation of rheumatoid factor activity. Asp-Phe methyl ester is being studied for its effect on thrombin activity and blood clotting.Methyl ester of aspartic acid/phenylalanine dipeptide. Promotes weight gain in vivo .
储存温度 2-8°C储存
运输条件 冰袋运输
备注 1g卖完停产,不再备货
产品介绍

微溶于水(约1%)和乙醇(0.26mg/100ml)。无臭、有强烈甜味,其稀溶液的甜度约为蔗糖的100-200倍。其甜味与砂糖十分相似,并有清凉感。0.8%水溶液的pH值为4-6.5。在水溶液中不稳定,易分解而失去甜味,低温时和pH值3-5时较稳定。 Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester

Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester

名称和标识符

EC号 245-261-3
IUPAC Name (3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
INCHI InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChi Key IAOZJIPTCAWIRG-QWRGUYRKSA-N
Canonical SMILES COC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC(=O)O)N
分子式

C14H18N2O5

PubChem CID 134601
Beilstein号 2223850
分子量 294.3

化学和物理性质

溶解性 Soluble in formic acid, dimethyl sulfoxide. Sparingly soluble in water and ethanol.
密度 1.28
熔点 248-250°C
比旋光度 14.5 ° (C=4, 15mol/L Formic Acid)

安全信息

WGK Germany 2
RTECS WM3407000
Reaxy-Rn 2223850
Merck Index 839
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

参考文献

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55. Fernanda de Matos Feijó,Cíntia Reis Ballard,Kelly Carraro Foletto,Bruna Aparecida Melo Batista,Alice Magagnin Neves,Maria Flávia Marques Ribeiro,Marcello Casaccia Bertoluci.  (2012-10-24)  Saccharin and aspartame, compared with sucrose, induce greater weight gain in adult Wistar rats, at similar total caloric intake levels..  Appetite,  60  ((1)):  (203-207).  [PMID:23088901]
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58. Soheila Kashanian,Mohammad Mehdi Khodaei,Fahimeh Kheirdoosh.  (2013-02-05)  In vitro DNA binding studies of Aspartame, an artificial sweetener..  Journal of photochemistry and photobiology. B, Biology,  120  ():  (104-110).  [PMID:23375483]
59. Pornrat Sinchaipanit,William L Kerr,Rungrat Chamchan.  (2013-04-16)  Effect of sweeteners and hydrocolloids on quality attributes of reduced-calorie carrot juice..  Journal of the science of food and agriculture,  93  ((13)):  (3304-3311).  [PMID:23585014]
60. Francesco Lai,Elena Pini,Francesco Corrias,Jacopo Perricci,Maria Manconi,Anna Maria Fadda,Chiara Sinico.  (2014-04-01)  Formulation strategy and evaluation of nanocrystal piroxicam orally disintegrating tablets manufacturing by freeze-drying..  International journal of pharmaceutics,  467  ((1-2)):  (27-33).  [PMID:24680963]
61. Paula Arbeláez,Francesc Borrull,Rosa Maria Marcé,Eva Pocurull.  (2015-07-23)  Trace-level determination of sweeteners in sewage sludge using selective pressurized liquid extraction and liquid chromatography-tandem mass spectrometry..  Journal of chromatography. A,  1408  ():  (15-21).  [PMID:26199101]
62. Taichi Koizumi,Tohru Terada,Ken-ichiro Nakajima,Masaki Kojima,Seizo Koshiba,Yoshitaka Matsumura,Kohei Kaneda,Tomiko Asakura,Akiko Shimizu-Ibuka,Keiko Abe,Takumi Misaka.  (2015-08-12)  Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor..  Scientific reports,  ():  (12947-12947).  [PMID:26263392]
63. Hanna Manninen,Nikita Durandin,Anu Hopia,Elina Vuorimaa-Laukkanen,Timo Laaksonen.  (2020-03-04)  Taste compound - Nanocellulose interaction assessment by fluorescence indicator displacement assay..  Food chemistry,  318  ():  (126511-126511).  [PMID:32126462]

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