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7-氨基-4-甲基香豆素(AMC)

规格或纯度: 98%
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A109915-250mg 250mg 现货 Stock Image
A109915-1g 1g 现货 Stock Image
A109915-5g 5g 现货 Stock Image
A109915-10g 10g 现货 Stock Image
A109915-25g 25g 现货 Stock Image
A109915-100g 100g 现货 Stock Image
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六元杂环化合物 香豆素类

基本描述

规格或纯度 98%
英文名称 7-Amino-4-methylcoumarin
别名 香豆素120; AMC
英文别名 Coumarin 120; 7-Amino-4-methyl-2H-chromen-2-one; AMC
生化机理 7-Amino-4-methylcoumarin is a coumarin derivative, which serves as a fluorescence reference standard to screen protease inhibitors.
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

用作激光染料。荧光标记试剂,用于痕量检测酶。

用于高效液相色谱标记

7-Amino-4-methylcoumarin has been used:

· to determine cathepsin B like- activity

· as a substrate for leucine aminopeptidase (LAP)?

· in chymotryptic assay

· as a standard to detect the activation of caspase-3 during

· sanguinarine-induced damage

· protection by human DEAD-box DDX3

7-Amino-4-methylcoumarin (AMC) is a well-known laboratory reagent employed in the preparation of fluorogenic AMC-based substrates for the detection of proteolytic enzyme activity. AMC has been utilized as a fluorescent probe to analyze glycoproteins' monosaccharides and N-linked oligosaccharides via chromatography and has been used as a laser dye. Recent research shows that AMC was extracted from an endophytic Xylaria fungal species and exhibited strong antibacterial and antifungal activities in vitro against Aspergillus, Candida, Escherichia, Staphylococcus, Salmonella and Vibrio species, among others. This product is also useful as a reference standard in enzymatic assays.
Fluorescent labeling reagent for trace determination of enzymes. Suitable as laser dye

名称和标识符

EC号 247-454-8
IUPAC Name 7-amino-4-methylchromen-2-one
INCHI InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
InChi Key GLNDAGDHSLMOKX-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)N
分子式

C10H9NO2

PubChem CID 92249
Beilstein号 142231
分子量 175.18

化学和物理性质

溶解性 Soluble in DMSO (10 mg/ml), and DMF.
密度 1.275
敏感性 对光敏感
熔点 223-226°C

安全信息

象形图
ghs07

Harmful

信号词 Warning
危险声明 H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
预防措施声明 P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319
WGK Germany 3
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

参考文献

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