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L-丙氨酰-L-谷氨酸盐

L-谷氨酰胺的稳定形式;常用于细胞培养
规格或纯度: 98%
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A107409-1g 1g 现货 Stock Image
A107409-5g 5g 现货 Stock Image
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A107409-100g 100g 现货 Stock Image
A107409-500g 500g 现货 Stock Image
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基本描述

规格或纯度 98%
英文名称 Ala-Gln
别名 力肽;丙氨酰-L-谷氨酰胺;L-丙氨酰-L-谷氨酸盐;丙谷二肽; 丙氨酰谷氨酰胺;丙氨酸-谷氨酰胺
英文别名 H-Ala-Gln-OH; L-Alanyl-L-glutamine; Glutamine-S;H-Ala-Gln-OH;Alanyl-glutamine
生化机理 L-谷氨酰胺的稳定形式。常用于细胞培养。Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals. Alanyl-glutamine also acts as an antioxidant (peroxide) and anti-apoptosis (LPS-induced) factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.
应用 在哺乳动物细胞培养基中可以作谷氨酸盐的替代物,加热灭菌过程中稳定。 L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture as alternative delivery forms of stabilized L-glutamine. The primary advantage of using L-alanylglutamine in place of L-glutamine is that it reduces the level of ammonia generated during cell culture
储存温度 室温
运输条件 常规运输
产品介绍

无臭;有引湿性。本品在水中易溶,在甲醇中几乎不溶或不溶;在冰醋酸中略溶。在哺乳动物细胞培养基中可以作谷氨酸盐的替代物,加热灭菌过程中稳定。 L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture as alternative delivery forms of stabilized L-glutamine. The primary advantage of using L-alanylglutamine in place of L-glutamine is that it reduces the level of ammonia generated during cell culture

L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture as alternative delivery forms of stabilized L-glutamine. The primary advantage of using L-alanylglutamine in place of L-glutamine is that it reduces the level of ammonia generated during cell culture

名称和标识符

IUPAC Name (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoic acid
INCHI InChI=1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
InChi Key HJCMDXDYPOUFDY-WHFBIAKZSA-N
Canonical SMILES CC(C(=O)NC(CCC(=O)N)C(=O)O)N
分子式

C8H15N3O4

PubChem CID 123935
Beilstein号 1(1)540
分子量 217.22

化学和物理性质

溶解性 溶于water, 最高浓度 (mg/mL): 21.72, 最高浓度(mM): 100
密度 1.305
沸点 615℃
熔点 213-217°C
比旋光度 +8.0 to +12.0 deg(C=5, H2O)
闪点(℉) 230°F
闪点(℃) >110℃

安全信息

Reaxy-Rn 2417888

参考文献

1. Hassell T et al..  (1991)  Growth inhibition in animal cell culture. The effect of lactate and ammonia..  Appl Biochem Biotechnol,  30  ():  (29-41).  [PMID:1952924]
2. G Biolo,G Toigo,B Ciocchi,R Situlin,F Iscra,A Gullo,G Guarnieri.  (1997-09-18)  Metabolic response to injury and sepsis: changes in protein metabolism..  Nutrition (Burbank, Los Angeles County, Calif.),  13  ((9 Suppl)):  (52S-57S).  [PMID:9290110]
3. Brandhorst H et al..  (2005)  Effect of stable glutamine compounds on porcine islet culture..  Transplant Proc,  37  (8):  (3519-20).  [PMID:16298648]
4. J Mühling,M Fuchs,C Fleck,A Sablotzki,M Krüll,M G Dehne,J Gonter,S Weiss,J Engel,G Hempelmann.  (2002-05-25)  Effects of arginine, L-alanyl-L-glutamine or taurine on neutrophil (PMN) free amino acid profiles and immune functions in vitro..  Amino acids,  22  ((1)):  (39-53).  [PMID:12025873]
5. John D Biggers,Lynda K McGinnis,J A Lawitts.  (2004-07-20)  Enhanced effect of glycyl-L-glutamine on mouse preimplantation embryos in vitro..  Reproductive biomedicine online,  ((1)):  (59-69).  [PMID:15257821]
6. D E Johns,K A Athanasiou.  (2007-06-26)  Improving culture conditions for temporomandibular joint disc tissue engineering..  Cells, tissues, organs,  185  ((4)):  (246-257).  [PMID:17587799]
7. Jing-Chen Liu,Hai-Tang Wang,Wei Wang.  (2009-01-15)  Protective effects of alanyl-glutamine on acute lung injury induced by lipopolysaccharide in rats..  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences,  33  ((12)):  (1095-1100).  [PMID:19141974]
8. Tony E Haynes,Peng Li,Xilong Li,Kazuhiro Shimotori,Hiroyuki Sato,Nick E Flynn,Junjun Wang,Darrell A Knabe,Guoyao Wu.  (2009-02-04)  L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes..  Amino acids,  37  ((1)):  (131-142).  [PMID:19189199]
9. Yu-Chen Hou,Man-Hui Pai,Jun-Jen Liu,Sung-Ling Yeh.  (2013-03-23)  Alanyl-glutamine resolves lipopolysaccharide-induced lung injury in mice by modulating the polarization of regulatory T cells and T helper 17 cells..  The Journal of nutritional biochemistry,  24  ((9)):  (1555-1563).  [PMID:23517911]
10. Yu-Chen Hou,Jun-Jen Liu,Man-Hui Pai,Shung-Sheng Tsou,Sung-Ling Yeh.  (2013-06-01)  Alanyl-glutamine administration suppresses Th17 and reduces inflammatory reaction in dextran sulfate sodium-induced acute colitis..  International immunopharmacology,  17  ((1)):  (1-8).  [PMID:23721689]
11. M L Alves da Silva,A R Costa-Pinto,A Martins,V M Correlo,P Sol,M Bhattacharya,S Faria,R L Reis,Nuno M Neves.  (2013-10-25)  Conditioned medium as a strategy for human stem cells chondrogenic differentiation..  Journal of tissue engineering and regenerative medicine,  ((6)):  (714-723).  [PMID:24155167]
12. Eder Ricardo Petry,Vinicius Fernandes Cruzat,Thiago Gomes Heck,Jaqueline Santos Moreira Leite,Paulo Ivo Homem de Bittencourt,Julio Tirapegui.  (2013-11-26)  Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: involvement of heat shock protein pathways..  Life sciences,  94  ((2)):  (130-136).  [PMID:24269578]
13. Hiroshi Ono,Noriko Motoi,Hiroko Nagano,Eisaku Miyauchi,Masaru Ushijima,Masaaki Matsuura,Sakae Okumura,Makoto Nishio,Tetsuro Hirose,Naohiko Inase,Yuichi Ishikawa.  (2014-03-05)  Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer..  Cancer medicine,  ((3)):  (632-642).  [PMID:24591352]
14. Rebecca Herzog,Thorsten O Bender,Andreas Vychytil,Katarzyna Bialas,Christoph Aufricht,Klaus Kratochwill.  (2014-05-24)  Dynamic O-linked N-acetylglucosamine modification of proteins affects stress responses and survival of mesothelial cells exposed to peritoneal dialysis fluids..  Journal of the American Society of Nephrology : JASN,  25  ((12)):  (2778-2788).  [PMID:24854264]
15. Jamie Rae Acosta,Claire Goldsbury,Claire Winnick,Andrew P Badrock,Stuart T Fraser,Angela S Laird,Thomas E Hall,Emily K Don,Jennifer A Fifita,Ian P Blair,Garth A Nicholson,Nicholas J Cole.  (2014-06-10)  Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells..  PloS one,  ((6)):  (e90572-e90572).  [PMID:24912067]
16. John E Baatz,Danforth A Newton,Ellen C Riemer,Chadrick E Denlinger,E Ellen Jones,Richard R Drake,Demetri D Spyropoulos.  (2014-07-02)  Cryopreservation of viable human lung tissue for versatile post-thaw analyses and culture..  In vivo (Athens, Greece),  28  ((4)):  (411-423).  [PMID:24982205]
17. Francesca Colazzo,Fahad Alrashed,Padmini Saratchandra,Ivan Carubelli,Adrian H Chester,Magdi H Yacoub,Patricia M Taylor,Pamela Somers.  (2014-08-13)  Shear stress and VEGF enhance endothelial differentiation of human adipose-derived stem cells..  Growth factors (Chur, Switzerland),  32  ((5)):  (139-149).  [PMID:25112491]
18. Silvia Colleoni,Cesare Galli,John Antony Gaspar,Kesavan Meganathan,Smita Jagtap,Jurgen Hescheler,Dimitra Zagoura,Susanne Bremer,Agapios Sachinidis,Giovanna Lazzari.  (2014-09-07)  A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system..  Toxicology letters,  231  ((1)):  (38-44).  [PMID:25192806]
19. Eiko Yoshida,Yumi Abiko,Yoshito Kumagai.  (2014-10-02)  Glutathione adduct of methylmercury activates the Keap1-Nrf2 pathway in SH-SY5Y cells..  Chemical research in toxicology,  27  ((10)):  (1780-1786).  [PMID:25271560]
20. D Schmid,C Grabmer,D Streif,T Lener,K Schallmoser,E Rohde.  (2014-10-22)  T-cell death, phosphatidylserine exposure and reduced proliferation rate to validate extracorporeal photochemotherapy..  Vox sanguinis,  108  ((1)):  (82-88).  [PMID:25333914]
21. Sergio B Sesia,Ralph Duhr,Carolina Medeiros da Cunha,Atanas Todorov,Stefan Schaeren,Elisabetta Padovan,Giulio Spagnoli,Ivan Martin,Andrea Barbero.  (2014-11-22)  Anti-inflammatory/tissue repair macrophages enhance the cartilage-forming capacity of human bone marrow-derived mesenchymal stromal cells..  Journal of cellular physiology,  230  ((6)):  (1258-1269).  [PMID:25413299]
22. Anthony P Leonard,Robert B Cameron,Jaime L Speiser,Bethany J Wolf,Yuri K Peterson,Rick G Schnellmann,Craig C Beeson,B?rbel Rohrer.  (2014-12-03)  Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning..  Biochimica et biophysica acta,  1853  ((2)):  (348-360).  [PMID:25447550]
23. I-C Chuang,M-S Huang,L-J Huang,S-H Chou,T-N Tsai,Y-C Chen,R-C Yang.  (2014-12-04)  Prophylactic inhalation of L-alanyl-L-glutamine enhances heat shock protein 72 and attenuates endotoxin-induced lung injury in rats..  Physiological research,  64  ((4)):  (505-512).  [PMID:25470514]
24. Vinicius Fernandes Cruzat,Kevin Noel Keane,Anita Lavarda Scheinpflug,Robson Cordeiro,Mario J Soares,Philip Newsholme.  (2015-01-01)  Alanyl-glutamine improves pancreatic β-cell function following ex vivo inflammatory challenge..  The Journal of endocrinology,  224  ((3)):  (261-271).  [PMID:25550445]
25. Erda Avriyanti,Nur Atik,Masataka Kunii,Naomi Furumoto,Tomohiko Iwano,Shin-Ichiro Yoshimura,Reiko Harada,Akihiro Harada.  (2015-02-03)  Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity..  Neuroscience research,  95  ():  (12-20).  [PMID:25639845]
26. Jen-Seng Huang,Chia-Lung Wu,Chung-Wei Fan,Wen-Hsiang Chen,Kun-Yun Yeh,Pei-Hung Chang.  (2015-03-25)  Intravenous glutamine appears to reduce the severity of symptomatic platinum-induced neuropathy: a prospective randomized study..  Journal of chemotherapy (Florence, Italy),  27  ((4)):  (235-240).  [PMID:25800685]
27. Manuela Buonanno,Sonia M De Toledo,Roger W Howell,Edouard I Azzam.  (2015-03-26)  Low-dose energetic protons induce adaptive and bystander effects that protect human cells against DNA damage caused by a subsequent exposure to energetic iron ions..  Journal of radiation research,  56  ((3)):  (502-508).  [PMID:25805407]
28. Siran Wang,Chiara E Ghezzi,James D White,David L Kaplan.  (2015-03-27)  Coculture of dorsal root ganglion neurons and differentiated human corneal stromal stem cells on silk-based scaffolds..  Journal of biomedical materials research. Part A,  103  ((10)):  (3339-3348).  [PMID:25809662]
29. Masahiko Terauchi,Go Ikeda,Kei Nishida,Atsushi Tamura,Satoshi Yamaguchi,Kiyoshi Harada,Nobuhiko Yui.  (2015-03-27)  Supramolecular Polyelectrolyte Complexes of Bone Morphogenetic Protein-2 with Sulfonated Polyrotaxanes to Induce Enhanced Osteogenic Differentiation..  Macromolecular bioscience,  15  ((7)):  (953-964).  [PMID:25810046]
30. Annelien Verfaillie,Hana Imrichova,Zeynep Kalender Atak,Michael Dewaele,Florian Rambow,Gert Hulselmans,Valerie Christiaens,Dmitry Svetlichnyy,Flavie Luciani,Laura Van den Mooter,Sofie Claerhout,Mark Fiers,Fabrice Journe,Ghanem-Elias Ghanem,Carl Herrmann,Georg Halder,Jean-Christophe Marine,Stein Aerts.  (2015-04-14)  Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state..  Nature communications,  ():  (6683-6683).  [PMID:25865119]
31. Jeerapond Leelawattanachai,Keon-Woo Kwon,Praveesuda Michael,Richard Ting,Ju-Young Kim,Moonsoo M Jin.  (2015-04-23)  Side-by-Side Comparison of Commonly Used Biomolecules That Differ in Size and Affinity on Tumor Uptake and Internalization..  PloS one,  10  ((4)):  (e0124440-e0124440).  [PMID:25901755]
32. Jun Fan,Lidong Wu,Guoping Li,Shaoyu Tao,Zhiyong Sheng,Qingyan Meng,Fengxin Li,Lijuan Yu,Li Li.  (2015-06-13)  Effects of enteral nutrition with parenteral glutamine supplementation on the immunological function in septic rats..  The British journal of nutrition,  113  ((11)):  (1712-1722).  [PMID:26067806]
33. Dave J Koss,Lianne Robinson,Anna Mietelska-Porowska,Anna Gasiorowska,Kristina Sep?i?,Tom Turk,Marcel Jaspars,Grazyna Niewiadomska,Roderick H Scott,Bettina Platt,Gernot Riedel.  (2015-06-14)  Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits..  Cellular and molecular life sciences : CMLS,  72  ((23)):  (4613-4632).  [PMID:26070304]
34. Georg Karpel-Massler,Ma?mouna Ba,Chang Shu,Marc-Eric Halatsch,Mike-Andrew Westhoff,Jeffrey N Bruce,Peter Canoll,Markus D Siegelin.  (2015-10-17)  TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo..  Oncotarget,  ((34)):  (36456-36471).  [PMID:26474387]
35. Sandra Laner-Plamberger,Thomas Lener,Doris Schmid,Doris A Streif,Tina Salzer,Michaela ?ller,Cornelia Hauser-Kronberger,Thorsten Fischer,Volker R Jacobs,Katharina Schallmoser,Mario Gimona,Eva Rohde.  (2015-11-12)  Mechanical fibrinogen-depletion supports heparin-free mesenchymal stem cell propagation in human platelet lysate..  Journal of translational medicine,  13  ():  (354-354).  [PMID:26554451]
36. A Bartolazzi,M Mottolese,A Vocaturo,G Vocaturo,A Bigotti,M Prat,G Atlante,P G Natali.  (1991-01-01)  Use of monoclonal antibodies in solid tumors diagnosis: the endometrial carcinoma..  Cytotechnology,  5 Suppl 1  ():  (35-40).  [PMID:1367118]
37. E Roth,G Ollenschlager,G Hamilton,A Simmel,K Langer,W Fekl,R Jakesz.  (1988-07-01)  Influence of two glutamine-containing dipeptides on growth of mammalian cells..  In vitro cellular & developmental biology : journal of the Tissue Culture Association,  24  ((7)):  (696-698).  [PMID:3397369]
38. A Christie,M Butler.  (1999-07-09)  The adaptation of BHK cells to a non-ammoniagenic glutamate-based culture medium..  Biotechnology and bioengineering,  64  ((3)):  (298-309).  [PMID:10397867]
39. M Holecek,F Skopec,L Sprongl,J Mráz,H Skalská,M Pecka.  (2002-05-25)  Effect of alanyl-glutamine on leucine and protein metabolism in irradiated rats..  Amino acids,  22  ((1)):  (95-108).  [PMID:12025876]
40. Brigitte Kircher,Günther Eibl,Barbara Enrich,Karla L?tzer,Manfred Herold,Dietger Niederwieser.  (2003-02-27)  The role of L-alanyl-L-glutamine in the immune response in vitro..  Wiener klinische Wochenschrift,  114  ((15-16)):  (702-708).  [PMID:12602115]
41. Daren K Heyland,Gunnar Elke,Deborah Cook,Mette M Berger,Paul E Wischmeyer,Martin Albert,John Muscedere,Gwynne Jones,Andrew G Day.  (2014-05-08)  Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial..  JPEN. Journal of parenteral and enteral nutrition,  39  ((4)):  (401-409).  [PMID:24803474]
42. Eun-ju Lee,Wei Luo,Eugene W L Chan,Muhammad N Yousaf.  (2015-06-02)  A molecular smart surface for spatio-temporal studies of cell mobility..  PloS one,  10  ((6)):  (e0118126-e0118126).  [PMID:26030281]
43. Dominique J P M Stumpel,Pauline Schneider,Rob Pieters,Ronald W Stam.  (2015-07-21)  The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia..  European journal of cancer (Oxford, England : 1990),  51  ((14)):  (2008-2021).  [PMID:26188848]

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