9(10H)-吖啶酮

规格或纯度: 98%

CAS编号: 578-95-0
分子式: C₁₃H₉NO
分子量: 195.22
Beilstein号: 7104
EC号: 209-434-7
MDL号: MFCD00005019
PubChem编号: 2015

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货号 (SKU)	包装规格	是否现货
A105216-1g	1g	现货
A105216-5g	5g	现货
A105216-10g	10g	现货
A105216-25g	25g	现货
A105216-100g	100g	现货

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六元杂环化合物吡啶类

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基本描述

规格或纯度	98%
英文名称	9(10H)-Acridanone
别名	吖啶酮
英文别名	acridone\|578-95-0\|9(10H)-Acridone\|acridin-9(10H)-one\|9-Acridone\|9(10H)-ACRIDINONE\|Acridanone\|10H-acridin-9-one\|9-Acridanone\|9(10H)-Acridanone\|Acridin-9-one\|9,10-Dihydro-9-oxoacridine\|Acridine, 9,10-dihydro-9-oxo-\|MFCD00005019\|9,10-dihydroacridin-9-one\|ACR
运输条件	常规运输
产品介绍	Acridone is useful in various pharmacological activities. Acridone acetic acid is one of the most important derivatives of acridone and is known as neovir, an antiviral drμg. Some of acridone's derivatives may be potentially used as antimalarial drμgs.A scaffold for the antiviral agent acridone acetic acid. Acridone is useful in various pharmacological activities. Acridone acetic acid is one of the most important derivatives of acridone and is known as neovir, an antiviral drug. Some of acridone's derivatives may be potentially used as antimalarial drugs. A scaffold for the antiviral agent acridone acetic acid.

名称和标识符

EC号	209-434-7
IUPAC Name	10H-acridin-9-one
INCHI	InChI=1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)
InChi Key	FZEYVTFCMJSGMP-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2
WGK Germany	3
RTECS	AR6976000
PubChem CID	2015
分子量	195.22
Beilstein号	7104
Reaxy-Rn	7104

化学和物理性质

溶解性	Soluble in DMF: 50 mg/ml Does not mix with water.
密度	1.23
熔点	361-362°C

安全和危险性（GHS）

象形图	Harmful
信号词	Warning
危险声明	H315: Causes skin irritation H319: Causes serious eye irritation
预防措施声明	P305+P351+P338,P280,P302+P352,P321,P264,P362+P364,P264+P265,P337+P317,P332+P317
WGK Germany	3
RTECS	AR6976000
Reaxy-Rn	7104
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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参考文献

1. Severino RP, Guido RV, Marques EF, Br?mme D, da Silva MF, Fernandes JB, Andricopulo AD, Vieira PC. (2011) Acridone alkaloids as potent inhibitors of cathepsin V.. Bioorg Med Chem, 19 (4): (1477-81). [PMID:21277783]
2. Hernandez-Olmos V, Abdelrahman A, El-Tayeb A, Freudendahl D, Weinhausen S, Müller CE. (2012) N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.. J Med Chem, 55 (22): (9576-88). [PMID:23075067]
3. Han Y, Luo A, Kamau PM, Takomthong P, Hu J, Boonyarat C, Luo L, Lai R. (2021) A plant-derived TRPV3 inhibitor suppresses pain and itch.. Br J Pharmacol, 178 (7): (1669-1683). [PMID:33501656]
4. Frederik B Pruijn,Joanna R Sturman,H D Sarath Liyanage,Kevin O Hicks,Michael P Hay,William R Wilson. (2005-02-18) Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer cultures.. Journal of medicinal chemistry, 48 ((4)): (1079-1087). [PMID:15715475]
5. Chunmei Gao,Yuyang Jiang,Chunyan Tan,Xuyu Zu,Huachen Liu,Derong Cao. (2008-08-21) Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones.. Bioorganic & medicinal chemistry, 16 ((18)): (8670-8675). [PMID:18713666]
6. Arnon Chukaew,Chanita Ponglimanont,Chatchanok Karalai,Supinya Tewtrakul. (2008-09-27) Potential anti-allergic acridone alkaloids from the roots of Atalantia monophylla.. Phytochemistry, 69 ((14)): (2616-2620). [PMID:18817938]
7. Hiroaki Ozaki,Yasuhisa Hagiwara,Hiromi Asakura,Masayasu Kuwahara. (2009-09-15) Acridone-labeled DNA aptamer for the detection of biomolecules.. Nucleic acids symposium series (2004), ((53)(53)): (255-256). [PMID:19749357]
8. Aleksandar Putic,Lambert Stecher,Helge Prinz,Klaus Müller. (2010-05-11) Structure-activity relationship studies of acridones as potential antipsoriatic agents. 1. Synthesis and antiproliferative activity of simple N-unsubstituted 10H-acridin-9-ones against human keratinocyte growth.. European journal of medicinal chemistry, 45 ((8)): (3299-3310). [PMID:20452101]
9. Vishal P Zambre,Prashant R Murumkar,Rajani Giridhar,Mange Ram Yadav. (2010-08-10) Development of highly predictive 3D-QSAR CoMSIA models for anthraquinone and acridone derivatives as telomerase inhibitors targeting G-quadruplex DNA telomere.. Journal of molecular graphics & modelling, 29 ((2)): (229-239). [PMID:20691626]
10. Olivier Mathieu,Olivier Dereure,Dominique Hillaire-Buys. (2010-11-23) Presence and ex vivo formation of acridone in blood of patients routinely treated with carbamazepine: exploration of the 9-acridinecarboxaldehyde pathway.. Xenobiotica; the fate of foreign compounds in biological systems, 41 ((2)): (91-100). [PMID:21087114]
11. O Arnaud,A Boumendjel,A Gèze,M Honorat,E L Matera,J Guitton,W D Stein,S E Bates,P Falson,C Dumontet,A Di Pietro,L Payen. (2011-01-11) The acridone derivative MBLI-87 sensitizes breast cancer resistance protein-expressing xenografts to irinotecan.. European journal of cancer (Oxford, England : 1990), 47 ((4)): (640-648). [PMID:21216589]
12. Jatinder Kaur,Palwinder Singh. (2011-03-08) ATP selective acridone based fluorescent probes for monitoring of metabolic events.. Chemical communications (Cambridge, England), 47 ((15)): (4472-4474). [PMID:21380453]
13. Florian Astelbauer,Andreas Obwaller,Adriane Raninger,Brigitte Brem,Harald Greger,Michael Duchêne,Walther Wernsdorfer,Julia Walochnik. (2011-03-23) Anti-leishmanial activity of plant-derived acridones, flavaglines, and sulfur-containing amides.. Vector borne and zoonotic diseases (Larchmont, N.Y.), 11 ((7)): (793-798). [PMID:21417924]
14. Magdalena Kukowska-Kaszuba,Krystyna Dzierzbicka,Marcin Serocki,Andrzej Skladanowski. (2011-03-24) Solid phase synthesis and biological activity of tuftsin conjugates.. Journal of medicinal chemistry, 54 ((7)): (2447-2454). [PMID:21425770]
15. Chinmay Pal,Milan Kumar Kundu,Uday Bandyopadhyay,Susanta Adhikari. (2011-05-24) Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation.. Bioorganic & medicinal chemistry letters, 21 ((12)): (3563-3567). [PMID:21600767]
16. Maizatul Akmal Yahayu,Mawardi Rahmani,Najihah Mohd Hashim,Muhammad Aizat Mohd Amin,Gwendoline Cheng Lian Ee,Mohd Aspollah Sukari,Abdah Akim. (2011-05-31) Two new acridone alkaloids from Glycosmis macrantha.. Molecules (Basel, Switzerland), 16 ((6)): (4401-4407). [PMID:21623311]
17. Jacob M Goldberg,Lee C Speight,Mark W Fegley,E James Petersson. (2012-04-05) Minimalist probes for studying protein dynamics: thioamide quenching of selectively excitable fluorescent amino acids.. Journal of the American Chemical Society, 134 ((14)): (6088-6091). [PMID:22471784]
18. Alessandra Di Veroli,Enzo Goretti,Miriam Le?n Paumen,Michiel H S Kraak,Wim Admiraal. (2012-04-21) Induction of mouthpart deformities in chironomid larvae exposed to contaminated sediments.. Environmental pollution (Barking, Essex : 1987), 166 (): (212-217). [PMID:22516711]
19. Pang-Chi Huang,Kanniyappan Parthasarathy,Chien-Hong Cheng. (2012-12-15) Copper-catalyzed intramolecular oxidative C-H functionalization and C-N formation of 2-aminobenzophenones: unusual pseudo-1,2-shift of the substituent on the aryl ring.. Chemistry (Weinheim an der Bergstrasse, Germany), 19 ((2)): (460-464). [PMID:23239266]
20. Vyry Na Wouatsa,Laxminarain Misra,Shiv Kumar,Om Prakash,Feroz Khan,Francois Tchoumbougnang,R Kumar Venkatesh. (2013-07-20) Aromatase and glycosyl transferase inhibiting acridone alkaloids from fruits of Cameroonian Zanthoxylum species.. Chemistry Central journal, 7 (): (125-125). [PMID:23866063]
21. Katarina Ulicna,Zuzana Bednarikova,Wei-Tse Hsu,Martina Holztragerova,Josephine W Wu,Slavka Hamulakova,Steven S-S Wang,Zuzana Gazova. (2018-03-20) Lysozyme amyloid fibrillization in presence of tacrine/acridone-coumarin heterodimers.. Colloids and surfaces. B, Biointerfaces, 166 (): (108-118). [PMID:29550545]
22. Peter A Segun,Fyaz M D Ismail,Omonike O Ogbole,Lutfun Nahar,Andrew R Evans,Edith O Ajaiyeoba,Satyajit D Sarker. (2018-09-07) Acridone alkaloids from the stem bark of Citrus aurantium display selective cytotoxicity against breast, liver, lung and prostate human carcinoma cells.. Journal of ethnopharmacology, 227 (): (131-138). [PMID:30189240]
23. María Jesús García-Galán,Larissa Arashiro,Lúcia H M L M Santos,Sara Insa,Sara Rodríguez-Mozaz,Damià Barceló,Ivet Ferrer,Marianna Garfí. (2020-03-05) Fate of priority pharmaceuticals and their main metabolites and transformation products in microalgae-based wastewater treatment systems.. Journal of hazardous materials, 390 (): (121771-121771). [PMID:32127240]
24. Alexander Vallmitjana,Alexander Dvornikov,Belen Torrado,David M Jameson,Suman Ranjit,Enrico Gratton. (2020-04-03) Resolution of 4 components in the same pixel in FLIM images using the phasor approach.. Methods and applications in fluorescence, 8 ((3)): (035001-035001). [PMID:32235070]
25. Nicola Montemurro,Anastasia Orfanioti,Rayana Manasfi,Nikolaos S Thomaidis,Sandra Pérez. (2020-10-02) Comparison of high resolution mrm and sequential window acquisition of all theoretical fragment-ion acquisition modes for the quantitation of 48 wastewater-borne pollutants in lettuce.. Journal of chromatography. A, 1631 (): (461566-461566). [PMID:33002708]
26. Giuseppe Manfroni,Jan Paeshuyse,Serena Massari,Samantha Zanoli,Barbara Gatto,Giovanni Maga,Oriana Tabarrini,Violetta Cecchetti,Arnaldo Fravolini,Johan Neyts. (2009-04-25) Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor.. Journal of medicinal chemistry, 52 ((10)): (3354-3365). [PMID:19388645]
27. Palwinder Singh,Jatinder Kaur,Bhawna Yadav,Sneha Sudha Komath. (2009-05-05) Design, synthesis and evaluations of acridone derivatives using Candida albicans--search for MDR modulators led to the identification of an anti-candidiasis agent.. Bioorganic & medicinal chemistry, 17 ((11)): (3973-3979). [PMID:19409796]
28. Francisco Cuenca,Michael J B Moore,Karin Johnson,Bérangère Guyen,Anne De Cian,Stephen Neidle. (2009-07-31) Design, synthesis and evaluation of 4,5-di-substituted acridone ligands with high G-quadruplex affinity and selectivity, together with low toxicity to normal cells.. Bioorganic & medicinal chemistry letters, 19 ((17)): (5109-5113). [PMID:19640709]
29. Markus Bacher,Günter Brader,Harald Greger,Otmar Hofer. (2009-11-26) Complete 1H and 13C NMR data assignment of new constituents from Severinia buxifolia.. Magnetic resonance in chemistry : MRC, 48 ((1)): (83-88). [PMID:19937908]
30. Aleksandar Putic,Lambert Stecher,Helge Prinz,Klaus Müller. (2010-09-21) Structure-activity relationship studies of acridones as potential antipsoriatic agents. 2. Synthesis and antiproliferative activity of 10-substituted hydroxy-10H-acridin-9-ones against human keratinocyte growth.. European journal of medicinal chemistry, 45 ((11)): (5345-5352). [PMID:20850910]
31. Emmanuel Ngeufa Happi,Alain Fran?ois Waffo,Jean Duplex Wansi,Bonaventure Tchaleu Ngadjui,Norbert Sewald. (2011-01-19) O-prenylated acridone alkaloids from the stems of Balsamocitrus paniculata (Rutaceae).. Planta medica, 77 ((9)): (934-938). [PMID:21243586]
32. Naoto Takahashi,Subehan,Shigetoshi Kadota,Yasuhiro Tezuka. (2012-04-03) Mechanism-based CYP2D6 inactivation by acridone alkaloids of Indonesian medicinal plant Lunasia amara.. Fitoterapia, 83 ((4)): (774-779). [PMID:22465502]
33. Emerson F Marques,Mauro A Bueno,Patrícia D Duarte,Larissa R S P Silva,Ariani M Martinelli,Caio Y dos Santos,Richele P Severino,Dieter Br?mme,Paulo C Vieira,Arlene G Corrêa. (2012-05-18) Evaluation of synthetic acridones and 4-quinolinones as potent inhibitors of cathepsins L and V.. European journal of medicinal chemistry, 54 (): (10-21). [PMID:22591648]
34. Atul Bhardwaj,Jatinder Kaur,Sai Kiran Sharma,Zhangjian Huang,Frank Wuest,Edward E Knaus. (2012-12-04) Hybrid fluorescent conjugates of COX-2 inhibitors: search for a COX-2 isozyme imaging cancer biomarker.. Bioorganic & medicinal chemistry letters, 23 ((1)): (163-168). [PMID:23200247]
35. Anton V Dubrovskiy,Richard C Larock. (2012-12-05) Synthesis of o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles by the reaction of hydrazones and arynes.. The Journal of organic chemistry, 77 ((24)): (11232-11256). [PMID:23206164]
36. Mei Lu,Yong Liu,Roy Helmy,Gary E Martin,Howard D Dewald,Hao Chen. (2015-08-06) Online Investigation of Aqueous-Phase Electrochemical Reactions by Desorption Electrospray Ionization Mass Spectrometry.. Journal of the American Society for Mass Spectrometry, 26 ((10)): (1676-1685). [PMID:26242804]
37. Pascal Schl?pfer,Peifen Zhang,Chuan Wang,Taehyong Kim,Michael Banf,Lee Chae,Kate Dreher,Arvind K Chavali,Ricardo Nilo-Poyanco,Thomas Bernard,Daniel Kahn,Seung Y Rhee. (2017-02-24) Genome-Wide Prediction of Metabolic Enzymes, Pathways, and Gene Clusters in Plants.. Plant physiology, 173 ((4)): (2041-2059). [PMID:28228535]
38. Yanheng Pan,ShuangShuang Cheng,Xin Yang,Jingyue Ren,Jingyun Fang,Chii Shang,Weihua Song,Lushi Lian,Xinran Zhang. (2017-03-28) UV/chlorine treatment of carbamazepine: Transformation products and their formation kinetics.. Water research, 116 (): (254-265). [PMID:28343060]
39. Wei Wang,Yaobin Lu,Haiping Luo,Guangli Liu,Renduo Zhang,Song Jin. (2018-04-08) A microbial electro-fenton cell for removing carbamazepine in wastewater with electricity output.. Water research, 139 (): (58-65). [PMID:29626730]
40. A B Martínez-Piernas,S Nahim-Granados,M I Polo-López,P Fernández-Ibá?ez,S Murgolo,G Mascolo,A Agüera. (2019-03-03) Identification of transformation products of carbamazepine in lettuce crops irrigated with Ultraviolet-C treated water.. Environmental pollution (Barking, Essex : 1987), 247 (): (1009-1019). [PMID:30823329]
41. Usha K Rout,A S Sanket,Brijesh S Sisodia,Pradyumna K Mohapatra,Sanghamitra Pati,Rajni Kant,Gaurav R Dwivedi. (2020-01-30) A Comparative Review on Current and Future Drug Targets Against Bacteria & Malaria.. Current drug targets, 21 ((8)): (736-775). [PMID:31995004]
42. Dadi Chen,Xiaoyu Zuo,Juan Li,Xitong Wang,Jie Liu. (2020-07-24) Carbon migration and metagenomic characteristics during anaerobic digestion of rice straw.. Biotechnology for biofuels, 13 (): (130-130). [PMID:32699553]
43. Consuelo Ripoll,Pilar Herrero-Foncubierta,Virginia Puente-Mu?oz,M Carmen Gonzalez-Garcia,Delia Miguel,Sandra Resa,Jose M Paredes,Maria J Ruedas-Rama,Emilio Garcia-Fernandez,Mar Roldan,Susana Rocha,Herlinde De Keersmaecker,Johan Hofkens,Miguel Martin,Juan M Cuerva,Angel Orte. (2021-03-07) Chimeric Drug Design with a Noncharged Carrier for Mitochondrial Delivery.. Pharmaceutics, 13 ((2)): (). [PMID:33673228]

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9(10H)-吖啶酮

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基本描述

名称和标识符

化学和物理性质

安全和危险性（GHS）

相关文档

质检报告COA

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产品问答

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