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acipimox
| 别名 | Olbetam® |
|---|---|
| Compound Class | Synthetic organic |
| 变动原因 | Acipimox is a nicotinic acid derivative. |
| Related Product | 阿西莫司 |
Summary
| 是否批准为药物？ | (UK (2003)) |
|---|---|
| IUPAC Name | 5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acid |
| 别名 | Olbetam® |
数据库链接
生物活性
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
|---|---|
| 关联靶标 | HCA2 receptor |
临床资料
| Summary of Clinical Use | Used as an adjunct or alternative treatment in hyperlipidemias of types IIb and IV in patients who have not responded adequately to other lipid-regulating drugs such as a statin or fibrate, and lifestyle changes (including diet, exercise, and weight reduction). Not approved by the US FDA or the EMA, but is approved by national regulatory agencies. |
|---|---|
| 作用机制与药效学效应 |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants |
结构
| Canonical SMILES | [O-][n+]1cc(ncc1C)C(=O)O |
|---|---|
| Isomeric SMILES | [O-][n+]1cc(ncc1C)C(=O)O |
| InChI | InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10) |
| InChI key | DJQOOSBJCLSSEY-UHFFFAOYSA-N |
危险品化学品经营许可证（带存储）