Farnesoid X receptor-β
Target Id | 604 |
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缩写名 | SHP2 |
家族 | 1H. Liver X receptor-like receptors |
基因和蛋白信息
Species | Transmembrane Domains | Amino Acids | Chromosomal Location | Gene Symbol | Gene Name |
---|---|---|---|---|---|
Human | 2 | 147 | 1p13.2 | NR1H5P | nuclear receptor subfamily 1 group H member 5, pseudogene |
Mouse | 2 | 505 | 3 F2.2 | Nr1h5 | nuclear receptor subfamily 1, group H, member 5 |
Rat | 2 | 147 | 2q34 | Nr1h5 | nuclear receptor subfamily 1, group H, member 5 |
数据库链接
Entrez Gene | 643609 (Hs) , 381463 (Mm) , 690430 (Rn) |
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OMIM | 3026618 (Hs) |
RefSeq Protein | NP_941060 (Mm) , NP_963913 (Mm) , NP_963916 (Mm) |
Ensembl Gene | ENSG00000227970 (Hs) , ENSMUSG00000048938 (Mm) , ENSRNOG00000023073 (Rn) |
RefSeq Nucleotide | NM_201619 (Mm) , NM_198658 (Mm) , NM_201622 (Mm) |
Protein GI | 170650696 (Mm) , 224589800 (Hs) |
作用于该靶标的配体
Ligand Id | Ligand | Ligand Type | Action on Target | 对应产品货号 | 产品名称 |
---|---|---|---|---|---|
2746 | lanosterol | Metabolite | Agonist | L130208 | 羊毛甾醇 |
2747 | vitamin D3 | Metabolite | Agonist | C105354 | 维生素D3 |
2748 | desmosterol | Metabolite | Agonist | H400267 | 3β-羟基-5,24-胆甾二烯 |
2802 | cholesten | Metabolite | Agonist | C608540 | cholesten |
参考文献
1. Tarantino LM, Feiner L, Alavizadeh A, Wiltshire T, Hurle B, Ornitz DM, Webber AL, Raper J, Lengeling A, Rowe LB et al.. (2000) A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5.. Genomics, 66 (1): (55-64). [PMID:10843805] |