Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Human	2	447	11p11.2	NR1H3	nuclear receptor subfamily 1 group H member 3
Mouse	2	445	2 50.52 cM	Nr1h3	nuclear receptor subfamily 1, group H, member 3
Rat	2	445	3q24	Nr1h3	nuclear receptor subfamily 1, group H, member 3

Entrez Gene	10062 (Hs) , 22259 (Mm) , 58852 (Rn)
OMIM	602423 (Hs)
UniProtKB	Q13133 (Hs) , Q62685 (Rn) , Q9Z0Y9 (Mm)
RefSeq Nucleotide	NM_001130102 (Hs) , NM_031627 (Rn) , NM_013839 (Mm) , NM_001177730 (Mm)
RefSeq Protein	NP_005684 (Hs) , NP_038867 (Mm) , NP_113815 (Rn)
Ensembl Gene	ENSG00000025434 (Hs) , ENSMUSG00000002108 (Mm) , ENSRNOG00000013172 (Rn)
Orphanet	123908 (Hs)
Protein GI	295148193 (Mm) , 353731060 (Hs) , 145279192 (Rn)
NURSA Receptor	10.1621/WD46UVPRKT (Hs)
CATH/Gene3D	3.30.50.10 (N/A)
ChEMBL Target	CHEMBL2808 (Hs) , CHEMBL2189152 (Mm) , CHEMBL4523336 (Rn)

Ligand Id	Ligand	Ligand Type	Action on Target	对应产品货号	产品名称
2742	22R-hydroxycholesterol	Metabolite	Agonist	C130203	胆固醇-5-烯-3β,22(S)-二醇
2750	24(S)-hydroxycholesterol	Metabolite	Agonist	C130207	胆固醇-5-烯-3β,24(S)-二醇
2751	24(S), 25-epoxycholesterol	Metabolite	Agonist	S491757	24(S),25-环氧胆固醇
2752	27-hydroxycholesterol	Metabolite	Agonist	C130177	胆固醇-(25R)-5-烯-3β,27-二醇
2309	paxilline	Synthetic organic	Agonist	P492254	蕈青霉素
2688	L-783483	Synthetic organic	Agonist	L611419	L-783483
2753	acetyl-podocarpic dimer	Synthetic organic	Agonist	A346580	乙酰基罗汉松酸酐
2754	GW3965	Synthetic organic	Agonist	G125976	GW3965,LXR激动剂
2755	T0901317	Synthetic organic	Agonist	T129709	T0901317,非LXR激动剂
7725	AZ12260493	Synthetic organic	Agonist	A413448	AZ876
8690	GSK2033	Synthetic organic	Antagonist	G288522	GSK2033,LXR拮抗剂
8692	SR9238	Synthetic organic	Inverse agonist	S288664	SR 9238,LXR反向激动剂
2748	desmosterol	Metabolite	Agonist	H400267	3β-羟基-5,24-胆甾二烯
10034	IMB-808	Synthetic organic	Partial agonist	I611036	IMB-808
10721	DRL-17822	Synthetic organic	Inhibition	D609972	DRL-17822

1. Tiberi M, Jarvie KR, Silvia C, Falardeau P, Gingrich JA, Godinot N, Bertrand L, Yang-Feng TL, Fremeau Jr RT, Caron MG.  (1991)  Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor..  Proc Natl Acad Sci USA,  88  (17):  (7491-5).  [PMID:1831904]