Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Human	2	460	19q13.3	NR1H2	nuclear receptor subfamily 1 group H member 2
Mouse	2	446	7 B3	Nr1h2	nuclear receptor subfamily 1, group H, member 2
Rat	2	446	1q22	Nr1h2	nuclear receptor subfamily 1, group H, member 2

Entrez Gene	7376 (Hs) , 58851 (Rn) , 22260 (Mm)
OMIM	600380 (Hs)
UniProtKB	P55055 (Hs) , Q62755 (Rn) , Q60644 (Mm)
RefSeq Nucleotide	NM_007121 (Hs) , NM_031626 (Rn) , NM_009473 (Mm)
RefSeq Protein	NP_009052 (Hs) , NP_033499 (Mm) , NP_113814 (Rn)
Ensembl Gene	ENSG00000131408 (Hs) , ENSMUSG00000060601 (Mm) , ENSRNOG00000019812 (Rn)
Protein GI	375331888 (Hs) , 13928862 (Rn) , 6678507 (Mm)
NURSA Receptor	10.1621/4Y2DTEP5D8 (Hs)
CATH/Gene3D	3.30.50.10 (N/A)
ChEMBL Target	CHEMBL4105785 (Rn) , CHEMBL2417346 (Mm) , CHEMBL4093 (Hs)

Ligand Id	Ligand	Ligand Type	Action on Target	对应产品货号	产品名称
2742	22R-hydroxycholesterol	Metabolite	Agonist	C130203	胆固醇-5-烯-3β,22(S)-二醇
2750	24(S)-hydroxycholesterol	Metabolite	Agonist	C130207	胆固醇-5-烯-3β,24(S)-二醇
2752	27-hydroxycholesterol	Metabolite	Agonist	C130177	胆固醇-(25R)-5-烯-3β,27-二醇
2751	24(S), 25-epoxycholesterol	Metabolite	Agonist	S491757	24(S),25-环氧胆固醇
2688	L-783483	Synthetic organic	Agonist	L611419	L-783483
2754	GW3965	Synthetic organic	Agonist	G125976	GW3965,LXR激动剂
2755	T0901317	Synthetic organic	Agonist	T129709	T0901317,非LXR激动剂
2753	acetyl-podocarpic dimer	Synthetic organic	Agonist	A346580	乙酰基罗汉松酸酐
7725	AZ12260493	Synthetic organic	Agonist	A413448	AZ876
8690	GSK2033	Synthetic organic	Antagonist	G288522	GSK2033,LXR拮抗剂
8692	SR9238	Synthetic organic	Inverse agonist	S288664	SR 9238,LXR反向激动剂
8693	GSK9772	Synthetic organic	Negative	G610737	GSK9772
2748	desmosterol	Metabolite	Agonist	H400267	3β-羟基-5,24-胆甾二烯
9625	rovazolac	Synthetic organic	Agonist	R613278	rovazolac
10034	IMB-808	Synthetic organic	Partial agonist	I611036	IMB-808
10035	compound 17l [PMID: 26288691]	Synthetic organic	Antagonist	E608787	2-[2-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]phenyl]isoindole-1,3-dione

1. O'Malley KL, Harmon S, Tang L, Todd RD.  (1992)  The rat dopamine D4 receptor: sequence, gene structure, and demonstration of expression in the cardiovascular system..  New Biol,  4  (2):  (137-46).  [PMID:1554689]