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CCR3

Target Id 60
缩写名 SHP2
家族 Chemokine receptors

基因和蛋白信息

Species Transmembrane Domains Amino Acids Chromosomal Location Gene Symbol Gene Name
Rat 7 359 8q32 Ccr3 C-C motif chemokine receptor 3
Human 7 355 3p21.31 CCR3 C-C motif chemokine receptor 3
Mouse 7 359 9 75.05 cM Ccr3 chemokine (C-C motif) receptor 3

作用于该靶标的配体

Ligand Id Ligand Ligand Type Action on Target 对应产品货号 产品名称
770 CCL13 Peptide Full agonist rp173645 CCL13
754 CCL15 Peptide Full agonist rp173647 CCL15
771 CCL2 Peptide Full agonist rp173653 CCL2
775 CCL24 Peptide Full agonist rp173666 CCL24
776 CCL26 Peptide Full agonist rp173670 CCL26
758 CCL5 Peptide Full agonist rp173681 CCL5
759 CCL7 Peptide Full agonist rp173683 CCL7
773 HIV-Tat Peptide Full agonist rp174223 HIV-Tat
769 CCL11 Peptide Full agonist rp173641 CCL11
769 CCL11 Peptide Full agonist rp173641 CCL11
787 CCL11 Peptide Full agonist
788 Met-Ckβ7 Peptide Antagonist rp174522 Met-Ckβ7
789 RO116-4875/608 Synthetic organic Antagonist R613233 RO116-4875/608
790 RO116-9132/238 Synthetic organic Antagonist R613234 RO116-9132/238
791 RO320-2947/001 Synthetic organic Antagonist R613240 RO320-2947/001
792 RO330-0802/001 Synthetic organic Antagonist R613243 RO330-0802/001
793 YM-355179 Synthetic organic Antagonist Y614924 YM-355179
794 [125I]CCL11 (human) Peptide Antagonist rp175051 [12?I]CCL11 (human)
795 [3H]banyu (I) Synthetic organic Inverse agonist
796 banyu (I) Synthetic organic Inverse agonist B607926 banyu (I)
3492 BMS compound 87b Synthetic organic Antagonist A608165 3-(3-acetylphenyl)-1-[3-[(2R,4S)-2-[(1S)-1-hydroxypropyl]-4-(phenylmethyl)piperidin-1-yl]propyl]urea
3530 SB328437 Synthetic organic Antagonist S275358 SB 328437(DMSO溶液)
764 [125I]CCL5 (human) Peptide Agonist rp175064 [12?I]CCL5 (human)
765 [125I]CCL7 (human) Peptide Agonist rp175065 [12?I]CCL7 (human)
772 CCL8 Peptide Full agonist rp173686 CCL8
773 HIV-Tat Peptide Agonist rp174223 HIV-Tat
835 CXCL10 Peptide Antagonist rp173758 CXCL10
836 CXCL11 Peptide Antagonist rp173761 CXCL11
837 CXCL9 Peptide Antagonist rp173796 CXCL9
3649 CCL28 Peptide Full agonist rp173673 CCL28
7679 AZD3778 Synthetic organic Antagonist A607865 AZD3778
4382 CCL18 Peptide Antagonist rp173650 CCL18
3536 UCB35625 Synthetic organic Antagonist U614613 UCB35625
9680 GW766994 Synthetic organic Antagonist G610772 GW766994
10653 lazucirnon Synthetic organic Antagonist L611461 lazucirnon

参考文献

1. Salvatore CA, Jacobson MA, Taylor HE, Linden J, Johnson RG.  (1993)  Molecular cloning and characterization of the human A3 adenosine receptor..  Proc Natl Acad Sci USA,  90  (21):  (10365-9).  [PMID:8234299]
2. Sajjadi FG, Firestein GS.  (1993)  cDNA cloning and sequence analysis of the human A3 adenosine receptor..  Biochim Biophys Acta,  1179  (1):  (105-7).  [PMID:8399349]
3. Murrison EM, Goodson SJ, Edbrooke MR, Harris CA.  (1996)  Cloning and characterisation of the human adenosine A3 receptor gene..  FEBS Lett,  384  (3):  (243-6).  [PMID:8617363]
4. Atkinson MR, Townsend-Nicholson A, Nicholl JK, Sutherland GR, Schofield PR.  (1997)  Cloning, characterisation and chromosomal assignment of the human adenosine A3 receptor (ADORA3) gene..  Neurosci Res,  29  (13):  (73-79).  [PMID:9293494]

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品牌简介

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