Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Human	24	1956	3p22.2	SCN10A	sodium voltage-gated channel alpha subunit 10
Rat	24	1956	8q32	Scn10a	sodium voltage-gated channel alpha subunit 10
Mouse	24	1958	9 71.33 cM	Scn10a	sodium channel, voltage-gated, type X, alpha

OMIM	604427 (Hs)
Entrez Gene	20264 (Mm) , 29571 (Rn) , 6336 (Hs)
UniProtKB	Q62968 (Rn) , Q6QIY3 (Mm) , Q9Y5Y9 (Hs)
RefSeq Protein	NP_006505 (Hs) , NP_058943 (Rn) , NP_033160 (Mm)
RefSeq Nucleotide	NM_006514 (Hs) , NM_017247 (Rn) , NM_009134 (Mm)
Ensembl Gene	ENSG00000185313 (Hs) , ENSMUSG00000034533 (Mm) , ENSRNOG00000032473 (Rn)
Protein GI	8394242 (Rn) , 328927029 (Mm) , 110835710 (Hs)
Orphanet	325976 (Hs)
DrugBank Target	Q9Y5Y9 (Hs)
ChEMBL Target	CHEMBL5451 (Hs) , CHEMBL4017 (Rn) , CHEMBL5158 (Mm)

Ligand Id	Ligand	Ligand Type	Action on Target	对应产品货号	产品名称
2619	batrachotoxin	Natural product	None	B336933	细菌毒素
2623	lidocaine	Synthetic organic	Pore blocker	L129221	利多卡因
2616	tetrodotoxin	Natural product	Pore blocker	T111387	河豚毒素
2626	veratridine	Natural product	None	V275475	藜芦定
5734	A-803467	Synthetic organic	None	A127941	A-803467,Na V 1.8通道阻滞剂
7472	lacosamide	Synthetic organic	Antagonist	L125374	拉科酰胺
8521	PF-01247324	Synthetic organic	Pore blocker	P612721	PF-01247324
10119	AM-6120	Peptide	Inhibition	rp173452	AM-6120
11864	PF-04885614	Synthetic organic	Inhibition	P288823	PF 04885614,NaV1.8通道阻滞剂
12002	ABBV-318	Synthetic organic	Inhibition	A607321	ABBV-318
12630	suzetrigine	Synthetic organic	Inhibition	S614271	suzetrigine

1. Chen R, Lewis KA, Perrin MH, Vale WW.  (1993)  Expression cloning of a human corticotropin-releasing-factor receptor..  Proc Natl Acad Sci USA,  90  (19):  (8967-71).  [PMID:7692441]

2. Vita N, Laurent P, Lefort S, Chalon P, Lelias JM, Kaghad M, Le Fur G, Caput D, Ferrara P.  (1993)  Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors..  FEBS Lett,  335  (1):  (1-5).  [PMID:8243652]