Species	Transmembrane Domains	Amino Acids	Chromosomal Location	Gene Symbol	Gene Name
Rat	7	357	15p14	Ptger2	prostaglandin E receptor 2
Human	7	358	14q22.1	PTGER2	prostaglandin E receptor 2
Mouse	7	362	14 22.68 cM	Ptger2	prostaglandin E receptor 2 (subtype EP2)

RefSeq Protein	NP_112350 (Rn) , NP_000947 (Hs) , NP_032990 (Mm)
UniProtKB	Q62928 (Rn) , P43116 (Hs) , Q62053 (Mm)
OMIM	176804 (Hs)
RefSeq Nucleotide	NM_000956 (Hs) , NM_031088 (Rn) , NM_008964 (Mm)
Entrez Gene	5732 (Hs) , 81752 (Rn) , 19217 (Mm)
Ensembl Gene	ENSG00000125384 (Hs) , ENSMUSG00000037759 (Mm) , ENSRNOG00000050968 (Rn)
Protein GI	13592031 (Rn) , 6679529 (Mm) , 31881630 (Hs)
dbSNP	rs17197 (Hs)
GPCRdb	pe2r2_human (Hs) , pe2r2_mouse (Mm) , pe2r2_rat (Rn)
UniProtKB ID/Entry name	PE2R2_HUMAN (Hs) , PE2R2_MOUSE (Mm) , PE2R2_RAT (Rn)
DrugBank Target	P43116 (Hs)
ChEMBL Target	CHEMBL1881 (Hs) , CHEMBL2488 (Mm) , CHEMBL4909 (Rn)

Ligand Id	Ligand	Ligand Type	Action on Target	对应产品货号	产品名称
1925	11-deoxy-PGE1	Metabolite	Full agonist	D334664	11-脱氧前列腺素E1
1925	11-deoxy-PGE1	Metabolite	Full agonist	D334664	11-脱氧前列腺素E1
1926	16,16-dimethyl-PGE2	Metabolite	Full agonist	D275015	16,16-二甲基前列腺素 E2
1912	17-phenyl-ω-trinor-PGE2	Metabolite	Full agonist	P336631	17-苯基-18,19,20-三去甲前列腺素 E?
1947	19(R)-OH-PGE2	Metabolite	Full agonist	R607080	19(R)-OH-PGE?
1947	19(R)-OH-PGE2	Metabolite	Full agonist	R607080	19(R)-OH-PGE?
1928	AH13205	Synthetic organic	Full agonist	A607466	AH13205
1928	AH13205	Synthetic organic	Full agonist	A607466	AH13205
1929	evatanepag	Synthetic organic	Full agonist	E610226	evatanepag
1913	MB-28767	Synthetic organic	Full agonist	M611751	MB-28767
1913	MB-28767	Synthetic organic	Full agonist	M611751	MB-28767
1930	rivenprost	Synthetic organic	Full agonist	R613209	rivenprost
1931	ONO-AE-248	Synthetic organic	Full agonist	O612529	ONO-AE-248
1932	ONO-AE1-259	Synthetic organic	Full agonist	O612525	ONO-AE1-259
1933	ONO-AE1-329	Synthetic organic	Full agonist	O612526	ONO-AE1-329
1881	PGD2	Metabolite	Full agonist
1881	PGD2	Metabolite	Full agonist
1882	PGE1	Natural product	Full agonist	P129960	前列腺素E1
1882	PGE1	Natural product	Full agonist	P129960	前列腺素E1
1883	PGE2	Metabolite	Full agonist	D133402	地诺前列酮
1883	PGE2	Metabolite	Full agonist	D133402	地诺前列酮
1883	PGE2	Metabolite	Full agonist	D133402	地诺前列酮
1884	PGF2α	Metabolite	Full agonist	T136386	前列腺素
1884	PGF2α	Metabolite	Full agonist	T136386	前列腺素
1888	U46619	Synthetic organic	Full agonist	U275847	9,11-二脱氧基-11α,9α-亚甲基环氧前列腺素 F2α
1888	U46619	Synthetic organic	Full agonist	U275847	9,11-二脱氧基-11α,9α-亚甲基环氧前列腺素 F2α
1916	[3H]PGE2	Synthetic organic	Full agonist
1916	[3H]PGE2	Synthetic organic	Full agonist
1916	[3H]PGE2	Synthetic organic	Full agonist
1892	butaprost (free acid form)	Synthetic organic	Full agonist	B347295	Butaprost，游离酸
1892	butaprost (free acid form)	Synthetic organic	Full agonist	B347295	Butaprost，游离酸
1893	carbacyclin	Synthetic organic	Full agonist	C345266	碳环素（碳环PGI 2）
1893	carbacyclin	Synthetic organic	Full agonist	C345266	碳环素（碳环PGI 2）
1917	cicaprost	Synthetic organic	Full agonist	C337616	西卡前列素
1895	iloprost	Synthetic organic	Full agonist	I275787	伊洛前列素
1895	iloprost	Synthetic organic	Full agonist	I275787	伊洛前列素
1895	iloprost	Synthetic organic	Full agonist	I275787	伊洛前列素
1934	isocarbacyclin	Synthetic organic	Full agonist	I611178	isocarbacyclin
1935	misoprostol (free acid form)	Synthetic organic	Full agonist
1936	misoprostol (methyl ester)	Synthetic organic	Full agonist	M121725	米索前列醇
1896	AH6809	Synthetic organic	Antagonist	A275394	AH 6809,EP1和EP2拮抗剂
1896	AH6809	Synthetic organic	Antagonist	A275394	AH 6809,EP1和EP2拮抗剂
1896	AH6809	Synthetic organic	Antagonist	A275394	AH 6809,EP1和EP2拮抗剂
5816	taprenepag	Synthetic organic	Full agonist	T412184	塔普雷内帕
5816	taprenepag	Synthetic organic	Full agonist	T412184	塔普雷内帕
1929	evatanepag	Synthetic organic	Full agonist	E610226	evatanepag
5817	PF-04418948	Synthetic organic	Antagonist	P286546	PF 04418948,EP2受体拮抗剂
5817	PF-04418948	Synthetic organic	Antagonist	P286546	PF 04418948,EP2受体拮抗剂
5818	TG4-155	Synthetic organic	Antagonist	T288898	TG 4-155,和EP2受体拮抗剂
5819	compound 1 [PMID: 20080612]	Synthetic organic	Positive	E608876	ethyl 2-(furan-2-carbonylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[d]thiophene-3-carboxylate
5820	treprostinil	Synthetic organic	Full agonist	T304716	(停产)曲前列尼尔(瑞莫杜林)
8538	PF-04852946	Synthetic organic	Antagonist	P612728	PF-04852946
8546	TG7-171	Synthetic organic	Antagonist	T614408	TG7-171
9283	TG6-129	Synthetic organic	Antagonist	T614407	TG6-129
1882	PGE1	Natural product	Full agonist	P129960	前列腺素E1
5852	MRE-269	Synthetic organic	Agonist	M413342	MRE-269 (ACT-333679)
10110	PGN-9856	Synthetic organic	Agonist	P612777	PGN-9856
10315	omidenepag	Synthetic organic	Agonist	O612502	omidenepag
10603	TG11-77	Synthetic organic	Antagonist	T614405	TG11-77
12520	TG8-260	Synthetic organic	Antagonist	T614409	TG8-260