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indoleamine 2,3-dioxygenase 1

Target Id 2829
缩写名 IDO1
家族 1.13.11.- Dioxygenases

基因和蛋白信息

Species Transmembrane Domains Amino Acids Chromosomal Location Gene Symbol Gene Name
Human 2 403 8p11.21 IDO1 indoleamine 2,3-dioxygenase 1
Mouse 2 407 8 A2 Ido1 indoleamine 2,3-dioxygenase 1
Rat 2 407 16q12.5 Ido1 indoleamine 2,3-dioxygenase 1

作用于该靶标的配体

Ligand Id Ligand Ligand Type Action on Target 对应产品货号 产品名称
8221 epacadostat Synthetic organic Inhibition E413870 Epacadostat (INCB024360)
8224 tryptanthrin Natural product Inhibition I302392 吲哚并[2,1-b]喹唑啉-6,12-二酮
8225 1-methyl-L-tryptophan Synthetic organic Inhibition M138479 1-甲基-L-色氨酸
8227 amg-1 Synthetic organic Inhibition A607600 amg-1
8222 beta-carboline Synthetic organic Inhibition N132898 9H-吡啶[3,4-b]吲哚
9019 navoximod Synthetic organic Inhibition N129887 919,小分子IDO途径抑制剂
9565 PF-06840003 Synthetic organic Inhibition P175464 PF-06840003,IDO-1 抑制剂
9750 necrostatin-1 Synthetic organic Inhibition N125522 Necrostatin-1,特异性坏死病抑制剂
9940 LW106 Synthetic organic Inhibition L611627 LW106
10126 tryptanthrin 5i Synthetic organic Inhibition T614564 tryptanthrin 5i
10126 tryptanthrin 5i Synthetic organic Inhibition T614564 tryptanthrin 5i
10682 compound 8u [PMID: 31999451] Synthetic organic Inhibition Z609475 (Z)-N-(3,5-Dimethoxyphenyl)-2-((4-(hydroxyimino)-1-oxo-1,4-dihydronaphthalen-2-yl) amino)-3-phenylpropanamide
9707 linrodostat Synthetic organic Inhibition L414088 Linrodostat (BMS-986205)

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品牌简介

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