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HCK proto-oncogene, Src family tyrosine kinase
| Target Id | 2032 |
|---|---|
| 缩写名 | Hck |
| 家族 | Src family |
基因和蛋白信息
数据库链接
| Ensembl Gene | ENSG00000101336 (Hs) , ENSMUSG00000003283 (Mm) , ENSRNOG00000009331 (Rn) |
|---|---|
| Entrez Gene | 3055 (Hs) , 15162 (Mm) , 25734 (Rn) |
| OMIM | 142370 (Hs) |
| UniProtKB | P08103 (Mm) , P08631 (Hs) , P50545 (Rn) |
| RefSeq Nucleotide | NM_001172129 (Hs) , NM_010407 (Mm) , NM_013185 (Rn) |
| RefSeq Protein | NP_002101 (Hs) , NP_034537 (Mm) , NP_037317 (Rn) |
| Protein GI | 30795229 (Hs) , 34734056 (Mm) , 34734058 (Rn) |
| CATH/Gene3D | 3.30.505.10 (N/A) |
| ChEMBL Target | CHEMBL3234 (Hs) |
作用于该靶标的配体
| Ligand Id | Ligand | Ligand Type | Action on Target | 对应产品货号 | 产品名称 |
|---|---|---|---|---|---|
| 8013 | PP121 | Synthetic organic | Inhibition | P126419 | PP121,酪氨酸和磷酸肌醇激酶的双重抑制剂 |
| 8136 | compound 2 [PMID: 15546730] | Synthetic organic | Inhibition | N609072 | N-(2-chloro-6-methylphenyl)-2-[(2,6-dimethylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide |
| 9186 | eCF506 | Synthetic organic | Inhibition | E412546 | eCF506 |
| 6912 | ibrutinib | Synthetic organic | Inhibition | P127143 | 依鲁替尼 (PCI-32765) |
| 9917 | pexmetinib | Synthetic organic | Inhibition | P413835 | Pexmetinib (ARRY-614) |
危险品化学品经营许可证（带存储）