protein kinase C zeta
Target Id | 1491 |
---|---|
缩写名 | PKCζ |
家族 | Iota subfamily |
基因和蛋白信息
数据库链接
Ensembl Gene | ENSG00000067606 (Hs) , ENSMUSG00000029053 (Mm) , ENSRNOG00000015480 (Rn) |
---|---|
Entrez Gene | 18762 (Mm) , 25522 (Rn) , 5590 (Hs) |
OMIM | 176982 (Hs) |
Protein GI | 11968080 (Rn) , 338968874 (Hs) , 84872205 (Mm) |
UniProtKB | P09217 (Rn) , Q02956 (Mm) , Q05513 (Hs) |
RefSeq Nucleotide | NM_001033581 (Hs) , NM_008860 (Mm) , NM_022507 (Rn) |
RefSeq Protein | NP_001028753 (Hs) , NP_001034168 (Mm) , NP_032886 (Mm) , NP_071952 (Rn) |
ChEMBL Target | CHEMBL3438 (Hs) |
作用于该靶标的配体
Ligand Id | Ligand | Ligand Type | Action on Target | 对应产品货号 | 产品名称 |
---|---|---|---|---|---|
2391 | arachidonic acid | Metabolite | Activation | A111764 | 花生四烯酸(AA) |
5192 | Gö 6983 | Synthetic organic | Inhibition | G129385 | Go 6983, 广谱PKC抑制剂 |
8142 | balanol | Natural product | Inhibition | B607920 | balanol |
8185 | compound 3 [PMID: 19097791] | Synthetic organic | Inhibition | M609187 | 2-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1H-indazol-6-yl}phenol |
参考文献
1. Drouet B, Garcia L, Simon-Chazottes D, Mattei MG, Guénet JL, Schwartz A, Varadi G, Pin?on-Raymond M. (1993) The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.. Mamm Genome, 4 (9): (499-503). [PMID:8118099] |