Proton-coupled Amino acid Transporter 1
Target Id | 1161 |
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缩写名 | PAT1 |
家族 | SLC36 family of proton-coupled amino acid transporters |
基因和蛋白信息
数据库链接
Ensembl Gene | ENSG00000123643 (Hs) , ENSMUSG00000020261 (Mm) , ENSRNOG00000012356 (Rn) |
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Entrez Gene | 215335 (Mm) , 155205 (Rn) , 206358 (Hs) |
OMIM | 606561 (Hs) |
Protein GI | 18426842 (Rn) , 145207965 (Mm) , 41352721 (Hs) |
UniProtKB | Q7Z2H8 (Hs) , Q8K4D3 (Mm) , Q924A5 (Rn) |
Bioparadigms SLC Tables | SLC36A1 (Hs) |
RESOLUTE | SLC36A1 (Hs) |
ChEMBL Target | CHEMBL1914279 (Hs) |
作用于该靶标的配体
Ligand Id | Ligand | Ligand Type | Action on Target | 对应产品货号 | 产品名称 |
---|---|---|---|---|---|
5 | 5-hydroxytryptamine | Metabolite | Inhibition | H303833 | 5-羟基色胺 |
717 | L-tryptophan | Metabolite | Inhibition | T118579 | L-色氨酸 |
4671 | 5-hydroxy-L-tryptophan | Metabolite | Inhibition | H111084 | 5-羟基色氨酸 |
4709 | indole-3-propionic acid | Natural product | Inhibition | I103959 | 3-吲哚丙酸(IPA) |
1013 | 17β-estradiol | Metabolite | Inhibition | ||
7071 | ethinylestradiol | Metabolite | Inhibition | E129595 | 炔雌醇 |
参考文献
1. Emberger W, Windpassinger C, Petek E, Kroisel PM, Wagner K. (2000) Assignment of the human GABAA receptor delta-subunit gene (GABRD) to chromosome band 1p36.3 distal to marker NIB1364 by radiation hybrid mapping.. Cytogenet Cell Genet, 89 (3-4): (281-2). [PMID:10965146] |
2. Sommer B, Poustka A, Spurr NK, Seeburg PH. (1990) The murine GABAA receptor delta-subunit gene: structure and assignment to human chromosome 1.. DNA Cell Biol, 9 (8): (561-8). [PMID:2176788] |