tolmetin
别名 | McN-2559-21-98, MCN-2559, Tolectin® |
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Compound Class | Synthetic organic |
变动原因 |
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic activity. Marketed formulations may contain tolmetin sodium (PubChem CID 23665411). |
Related Product | 托麦汀 |
Summary
是否批准为药物? | (FDA (1976)) |
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IUPAC Name | 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid |
别名 | McN-2559-21-98, MCN-2559, Tolectin® |
数据库链接
生物活性
生物活性评价 | We have been unable to find publicly available affinity data for this drug to substantiate its MMOA and have therefore not tagged a primary drug target. |
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临床资料
Summary of Clinical Use | Used to relieve the symptoms of osteo- and rheumatoid arthritis. |
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作用机制与药效学效应 | As with other NSAIDs, this drug reduces prostaglandin synthesis by reducing cyclooxegenase (COX) activity. |
结构
Canonical SMILES | OC(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C |
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Isomeric SMILES | OC(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C |
InChI | InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) |
InChI key | UPSPUYADGBWSHF-UHFFFAOYSA-N |