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tolmetin

别名 McN-2559-21-98, MCN-2559, Tolectin®
Compound Class Synthetic organic
变动原因 Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic activity.
Marketed formulations may contain tolmetin sodium (PubChem CID 23665411).

Summary

是否批准为药物? (FDA (1976))
IUPAC Name 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
别名 McN-2559-21-98, MCN-2559, Tolectin®

生物活性

生物活性评价 We have been unable to find publicly available affinity data for this drug to substantiate its MMOA and have therefore not tagged a primary drug target.

临床资料

Summary of Clinical Use Used to relieve the symptoms of osteo- and rheumatoid arthritis.
作用机制与药效学效应 As with other NSAIDs, this drug reduces prostaglandin synthesis by reducing cyclooxegenase (COX) activity.

结构

Canonical SMILES OC(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C
Isomeric SMILES OC(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C
InChI InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18)
InChI key UPSPUYADGBWSHF-UHFFFAOYSA-N

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品牌简介

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