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amylin
| Compound Class | Peptide |
|---|---|
| 变动原因 |
Amylin acts as an appetite suppressor. Novo Nordisk have a long-acting amylin mimetic (AM833, NNC0174-0833) in clinical trials with and without |
| Species |
Human |
| Related Product | Amylin, amide, rat acetate |
Summary
| 基因/前体 |
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| 是否批准为药物？ | |||||||||||
| IUPAC Name | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
数据库链接
| UniProtKB | P10997 |
|---|---|
| CAS Registry No. | 122384-88-7 |
| Ensembl Gene | ENSG00000121351 |
| Entrez Gene | 3375 |
| Wikipedia | Amylin |
| GPCRdb Ligand | 687 |
生物活性
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
|---|---|
| 关联靶标 | CT receptor , AMY1 receptor , AMY2 receptor , AMY3 receptor |
临床资料
| 作用机制与药效学效应 |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants |
|---|
结构
| Peptide Sequence | KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY |
|---|---|
| Post Translation Modifications | The C-terminal proline is amidated into Pro-NH2 and a disulphide bridge is formed between cysteine residues at positions 2 and 7. |
危险品化学品经营许可证（带存储）