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placental growth factor
| 别名 | PIGF |
|---|---|
| Compound Class | Peptide |
| 变动原因 | Biologically active placental growth factor is an antiparellel homodimer |
| Species |
Human |
| Related Product | placental growth factor |
Summary
| 基因/前体 |
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| 是否批准为药物？ | |||||||||||
| IUPAC Name | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
| 别名 | PIGF |
数据库链接
| Wikipedia | Placental_growth_factor |
|---|---|
| UniProtKB | P49763 |
| Ensembl Gene | ENSG00000119630 |
| DrugBank Target | P49763 |
| CATH/Gene3D | 2.10.90.10 |
生物活性
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
|---|
临床资料
| 作用机制与药效学效应 |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants |
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结构
| Peptide Sequence | LPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRCECRHSPGRQSPDMPGDFRADAPSFLPPRRSLPMLFRMEWGCALTGSQSAVWPSSPVPEEIPRMHPGRNGKKQQRKPLREKMKPERCGDAVPRR |
|---|---|
| Post Translation Modifications | Interchain disulphide bonds between cysteine residues at positions 77 ad 86; intrachain disulphide bonds between cysteine residues at positions 34 and 76, 65 and 110, and 69 and 112. Predicted N-linked glycosylation on asparagine residues at positions 15 and 83 |
危险品化学品经营许可证（带存储）