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VEGFE

别名 PDGF-C, fallotein, spinal cord-derived growth factor, VEGF-E, PDGFC
Compound Class Peptide
变动原因 The exact sequence of the receptor-binding form of this peptide has not been established.
Species Human

Summary

基因/前体
Gene symbol Gene name Precursor protein name Species 别名
PDGFC platelet derived growth factor C prepro-platelet-derived growth factor C Human SCDGF, fallotein
是否批准为药物?
IUPAC Name 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
别名 PDGF-C, fallotein, spinal cord-derived growth factor, VEGF-E, PDGFC

生物活性

生物活性评价 The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).
关联靶标 kinase insert domain receptor , fms related receptor tyrosine kinase 4

临床资料

作用机制与药效学效应 Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants . The antibacterial MMOA is competitive inhibition of bacterial dihydropteroate synthase (DHPS) resulting in a block of folate biosynthesis .

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品牌简介

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