IFN-α7
别名 | IFN-alpha-7, interferon alpha-J, interferon alpha-J1, interferon alpha-7 |
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Compound Class | Peptide |
变动原因 | IFN-α7 is a type I IFN. |
Species |
Human |
Related Product | IFN-α7 |
Summary
基因/前体 |
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是否批准为药物? | |||||||||||
IUPAC Name | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide | ||||||||||
别名 | IFN-alpha-7, interferon alpha-J, interferon alpha-J1, interferon alpha-7 |
数据库链接
UniProtKB | P01567 |
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Wikipedia | IFNA7 |
Ensembl Gene | ENSG00000214042 |
生物活性
生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
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关联靶标 | Interferon-α/β receptor |
临床资料
作用机制与药效学效应 |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants |
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结构
Peptide Sequence | CDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTNLKKGLRRKD |
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Post Translation Modifications | Predicted disulphide bond formation between cysteine residues at positions 1 and 99, and 29 and 139 |