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FGF-9

别名 FGF-9, glia-activating factor (GAF), heparin-binding growth factor 9 (HBGF-9)
Compound Class Peptide
变动原因 Monomer and homodimer
Species Human

Summary

基因/前体
Gene symbol Gene name Precursor protein name Species 别名
FGF9 fibroblast growth factor 9 prepro-fibroblast growth factor 9 Human fibroblast growth factor 9 (glia-activating factor)
是否批准为药物?
IUPAC Name 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
别名 FGF-9, glia-activating factor (GAF), heparin-binding growth factor 9 (HBGF-9)

生物活性

生物活性评价 The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in ).

临床资料

作用机制与药效学效应 Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants . The antibacterial MMOA is competitive inhibition of bacterial dihydropteroate synthase (DHPS) resulting in a block of folate biosynthesis .

结构

Peptide Sequence LGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS
Post Translation Modifications Predicted N-linked glycosylation of asparagine residue at position 76

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品牌简介

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