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phloretin
| Compound Class | Natural product |
|---|---|
| 变动原因 | Found in apple tree leaves and in the Manchurian apricot. Another naturally occuring organic molecule, phlorizin, which is found in the bark of several types of fruit tree, is converted into phloretin in the body by hydrolytic enzymes. |
| Related Product | 根皮素 |
Summary
| 是否批准为药物？ | |
|---|---|
| IUPAC Name | 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one |
数据库链接
| DrugBank Ligand | DB07810 |
|---|---|
| Wikipedia | Phloretin |
| CAS Registry No. | 60-82-2 |
| PubChem CID | 4788 |
| ChEBI | CHEBI:17276 |
| ChEMBL Ligand | CHEMBL45068 |
| BitterDB Ligand | 909 |
| RCSB PDB Ligand | G50 |
生物活性
| 生物活性评价 |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic agents and have a broad spectrum of activity against both Gram-positive and Gram-negative species of bacteria (reviewed in |
|---|---|
| 关联靶标 | AQP9 , ClC-3 , Sodium-dependent vitamin C transporter 1 , major facilitator superfamily domain containing 4B , TAS2R14 , TAS2R39 |
临床资料
| 作用机制与药效学效应 |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants |
|---|
结构
| Canonical SMILES | Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O |
|---|---|
| Isomeric SMILES | Oc1ccc(cc1)CCC(=O)c1c(O)cc(cc1O)O |
| InChI | InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 |
| InChI key | VGEREEWJJVICBM-UHFFFAOYSA-N |
危险品化学品经营许可证（带存储）